Introduction: Statins reduce the risk of cardiovascular morbidity and mortality in patients with
or at risk for cardiovascular disease and their use is expanding, especially in elderly. Statins …

Drug–drug interactions (DDI) occurring with potentially inappropriate medications (PIM) are
additional risk factors that may increase the inappropriate character of PIM. The aim of this …

Statins are among the most commonly prescribed drugs, and around every fourth person
above the age of 40 is on statin medication. Therefore, it is of utmost clinical importance to …

Background The co-administration of drugs known to interact greatly impacts morbidity,
mortality, and health economics. This study aims to examine the drug–drug interaction (DDI) …

Abstract Background Drug–drug interactions (DDIs) can lead to medication-related harm,
and the older population is at greatest risk. We conducted a systematic review and meta …

Age is an independent risk factor for cardiovascular disease. With the accelerated growth of
the population of older adults, geriatric and cardiac care are becoming increasingly …

Importance Guidelines recommend targeting preventive interventions toward older adults
whose life expectancy is greater than the intervention's time to benefit (TTB). The TTB for …

Background: Polypharmacy is associated with a poor prognosis in the elderly, however,
information on the association of polypharmacy with cardiovascular outcomes in heart …

OBJECTIVES To identify the top priority areas for research to optimize pharmacotherapy in
older adults with cardiovascular disease (CVD). DESIGN Consensus meeting. SETTING …

Objectives We aimed to establish an explicit list of potentially clinically significant drug-drug
interactions (DDIs) in people aged≥ 65 years. Design A preliminary list of potentially …