Antimicrobial peptides (AMPs): A promising class of antimicrobial compounds

M Erdem Büyükkiraz, Z Kesmen - Journal of applied …, 2022 - academic.oup.com
Antimicrobial peptides (AMPs) are compounds, which have inhibitory activity against
microorganisms. In the last decades, AMPs have become powerful alternative agents that …

The multifaceted nature of antimicrobial peptides: Current synthetic chemistry approaches and future directions

BH Gan, J Gaynord, SM Rowe, T Deingruber… - Chemical Society …, 2021 - pubs.rsc.org
Bacterial infections caused by 'superbugs' are increasing globally, and conventional
antibiotics are becoming less effective against these bacteria, such that we risk entering a …

Design, optimization, and nanotechnology of antimicrobial peptides: From exploration to applications

P Tan, H Fu, X Ma - Nano Today, 2021 - Elsevier
Antibiotic resistance caused by antibiotic abuse, especially the emergence of multi-drug
resistant bacteria, poses a serious threat to human health, and makes it imperative to find …

Antimicrobial peptides as therapeutic agents: Opportunities and challenges

M Mahlapuu, C Björn, J Ekblom - Critical reviews in biotechnology, 2020 - Taylor & Francis
The rapid development of microbial resistance to conventional antibiotics has accelerated
efforts to find anti-infectives with a novel mode-of-action, which are less prone to bacterial …

Plant antimicrobial peptides: structures, functions, and applications

J Li, S Hu, W Jian, C Xie, X Yang - Botanical Studies, 2021 - Springer
Antimicrobial peptides (AMPs) are a class of short, usually positively charged polypeptides
that exist in humans, animals, and plants. Considering the increasing number of drug …

Antimicrobial peptides as anticancer agents: functional properties and biological activities

AL Tornesello, A Borrelli, L Buonaguro, FM Buonaguro… - Molecules, 2020 - mdpi.com
Antimicrobial peptides (AMPs), or host defense peptides, are small cationic or amphipathic
molecules produced by prokaryotic and eukaryotic organisms that play a key role in the …

Recent advances in design of antimicrobial peptides and polypeptides toward clinical translation

Y Jiang, Y Chen, Z Song, Z Tan, J Cheng - Advanced Drug Delivery …, 2021 - Elsevier
The recent outbreaks of infectious diseases caused by multidrug-resistant pathogens have
sounded a piercing alarm for the need of new effective antimicrobial agents to guard public …

Antimicrobial peptides under clinical investigation

HB Koo, J Seo - Peptide Science, 2019 - Wiley Online Library
Overuse of conventional antibiotics as well as the slow pace of new antibiotic drug
development leads to antimicrobial resistance (AMR). Because infections with multi‐drug …

Antimicrobial resistance and recent alternatives to antibiotics for the control of bacterial pathogens with an emphasis on foodborne pathogens

YA Helmy, K Taha-Abdelaziz, HAEH Hawwas, S Ghosh… - Antibiotics, 2023 - mdpi.com
Antimicrobial resistance (AMR) is one of the most important global public health problems.
The imprudent use of antibiotics in humans and animals has resulted in the emergence of …

[HTML][HTML] Mechanisms and consequences of bacterial resistance to antimicrobial peptides

DI Andersson, D Hughes… - Drug Resistance Updates, 2016 - Elsevier
Cationic antimicrobial peptides (AMPs) are an intrinsic part of the human innate immune
system. Over 100 different human AMPs are known to exhibit broad-spectrum antibacterial …