Prostate specific membrane antigen (PSMA), is a unique membrane bound glycoprotein,
which is overexpressed manifold on prostate cancer as well as neovasculature of most of …

Abstract The Na+/I− symporter (NIS) is an integral plasma membrane glycoprotein that
mediates active I− transport into the thyroid follicular cells, the first step in thyroid hormone …

Tumours progress through a cascade of events that enable the formation of metastases.
Some of the components that are required for this fatal process are well established …

Limited endoproteolysis of inactive precursor proteins at sites marked by paired or multiple
basic amino acids is a widespread process by which biologically active peptides and …

▪ Abstract Clathrin was discovered nearly 25 years ago. Since then, a large number of other
proteins that participate in the process by which clathrin-coated vesicles retrieve synaptic …

Hermansky-Pudlak syndrome (HPS) is a genetic disorder characterized by defective
lysosome-related organelles. Here, we report the identification of two HPS patients with …

Lysosomes are membrane‐bound cytoplasmic organelles involved in intracellular protein
degradation. They contain an assortment of soluble acid‐dependent hydrolases and a set of …

▪ Abstract There has recently been considerable progress in understanding the regulation of
clathrin-coated vesicle (CCV) formation and function. These advances are due to the …

Progesterone receptor membrane component 1 (PGRMC1) contains a cytochrome b5
domain fold and belongs to the so-called membrane-associated progesterone receptor …

▪ Abstract The modification of proteins by chains of ubiquitin has long been known to
mediate targeting of cytosolic and nuclear proteins for degradation by proteasomes. In this …