Different immunoregulation roles of activin A compared with TGF-β
F Li, Y Long, X Yu, Y Tong, L Gong - Frontiers in Immunology, 2022 - frontiersin.org
Activin A, a critical member of the transforming growth factor-β (TGF-β) superfamily, is a
pluripotent factor involved in allergies, autoimmune diseases, cancers and other diseases …
pluripotent factor involved in allergies, autoimmune diseases, cancers and other diseases …
Acute pancreatitis: pathogenesis and emerging therapies
S Zaman, F Gorelick - Journal of pancreatology, 2024 - journals.lww.com
Acute pancreatitis is a severe inflammatory disorder with limited treatment options. Improved
understanding of disease mechanisms has led to new and potential therapies. Here we …
understanding of disease mechanisms has led to new and potential therapies. Here we …
Non-canonical activin A signaling stimulates context-dependent and cellular-specific outcomes in CRC to promote tumor cell migration and immune tolerance
Simple Summary The identification of markers of metastatic disease is critical to improving
colorectal cancer survival rates. Activin A plays a critical role in tumor and immune cells in …
colorectal cancer survival rates. Activin A plays a critical role in tumor and immune cells in …
Role of stromal activin A in human pancreatic cancer and metastasis in mice
Pancreatic ductal adenocarcinoma (PDAC) has extensive stromal involvement and remains
one of the cancers with the highest mortality rates. Activin A has been implicated in colon …
one of the cancers with the highest mortality rates. Activin A has been implicated in colon …
Oral subacute nephrotoxicity of aristololactam I in rats
C Wang, Y Zhang, D Chen, H Weng, H Li, Y Lu - Toxicology, 2022 - Elsevier
Aristolactams (ALs) have been recognized as one kind of metabolites of aristolochic acids
(AAs), the nephrotoxic components of Aristolochiaceae plants, and are more widely …
(AAs), the nephrotoxic components of Aristolochiaceae plants, and are more widely …
Acute pancreatitis: Current clinical approaches, molecular pathophysiology, and potential therapeutics
Objective Severe acute pancreatitis (SAP), pancreatic inflammation leading to multiorgan
failure, is associated with high morbidity and mortality. There is a critical need to identify …
failure, is associated with high morbidity and mortality. There is a critical need to identify …
Nano‐curcumin supplementation in patients with mild and moderate acute pancreatitis: A randomized, placebo‐controlled trial
We aimed to investigate whether nano‐curcumin as an anti‐inflammatory agent is effective
in patients with mild and moderate AP. This study was a double‐blind, parallel‐arm …
in patients with mild and moderate AP. This study was a double‐blind, parallel‐arm …
Activin A signaling stimulates neutrophil activation and macrophage migration in pancreatitis
Acute Pancreatitis (AP) is associated with high mortality and current treatment options are
limited to supportive care. We found that blockade of activin A (activin) in mice improves …
limited to supportive care. We found that blockade of activin A (activin) in mice improves …
Dynamic Changes in Serum Cytokine Profile in Rats with Severe Acute Pancreatitis
R Zhou, W Bu, Y Fan, Z Du, J Zhang, S Zhang, J Sun… - Medicina, 2023 - mdpi.com
Background and Objectives: Most published research has only investigated a single
timepoint after the onset of severe acute pancreatitis (SAP), meaning that they have been …
timepoint after the onset of severe acute pancreatitis (SAP), meaning that they have been …
[HTML][HTML] Activin A as a Potential Biomarker for Preserved Ratio Impaired Spirometry (PRISm) and Clinical Outcomes in Community-Dwelling Adults
CY Sun, WJ Lee, HC Shen, WK Yu, WC Chen… - Archives of Gerontology …, 2024 - Elsevier
Introduction: This study endeavors to decipher the association between Activin A and
PRISm, thereby addressing the potential of Activin A as a serum biomarker for early …
PRISm, thereby addressing the potential of Activin A as a serum biomarker for early …