Covering: up to August 2015 Alkaloids account for some of the most beautiful and
biologically active natural products. Although they are usually classified along biosynthetic …

The sulfonamide is an important functional group. The sulfonamides have been extensively
used as pharmaceutical and agricultural agents because of their diverse biological …

A highly stereoselective joint total synthesis of the potent polyketide macrolide antibiotics
etnangien and etnangien methyl ester was accomplished by a convergent strategy and …

Cyclic sulfonamides (sultams) play a unique role in drug discovery and synthetic chemistry.
A direct synthesis of sultams by an intramolecular C (sp3)–H amidation reaction using an …

Natural products are embedded with structural motifs that inspire practitioners of synthetic
organic chemistry. The development of new synthetic methods and strategies for the …

This chapter deals with the formation of carbon‐nitrogen bonds by reaction of carbon
nucleophiles with electrophilic aminating reagents. The former encompass aliphatic and …

The synthesis of enantiopure cyclic nitrones has become a frequently addressed topic in
discussions of their usefulness in the production of natural products and biologically active …

Quantum mechanical calculations have been used to study the intramolecular additions of
hydroxylamines to alkenes and alkynes (“reverse Cope eliminations”). In intermolecular …

Bridge-containing segments exist in numerous natural products and active pharmaceutical
ingredients (API) and intermediates, creating more structural complexity. In addition, bridge …

The unique reactivity profile of α-chloronitroso derivatives is expressed to its fullest potential
through the development of an integrated, modular and scalable continuous flow process for …