Thrombotic thrombocytopenic purpura: pathophysiology, diagnosis, and management

S Sukumar, B Lämmle, SR Cataland - Journal of clinical medicine, 2021 - mdpi.com
Thrombotic thrombocytopenic purpura (TTP) is a rare thrombotic microangiopathy
characterized by microangiopathic hemolytic anemia, severe thrombocytopenia, and …

Guidelines on the use of therapeutic apheresis in clinical practice–evidence‐based approach from the writing committee of the American society for apheresis: the …

J Schwartz, A Padmanabhan, N Aqui… - Journal of clinical …, 2016 - Wiley Online Library
The American Society for Apheresis (ASFA) Journal of Clinical Apheresis (JCA) Special
Issue Writing Committee is charged with reviewing, updating, and categorizing indications …

Guidelines on the use of therapeutic apheresis in clinical practice–evidence‐based approach from the Writing Committee of the American Society for Apheresis: the …

A Padmanabhan, L Connelly‐Smith… - Journal of clinical …, 2019 - Wiley Online Library
ABSTRACT The American Society for Apheresis (ASFA) Journal of Clinical Apheresis (JCA)
Special Issue Writing Committee is charged with reviewing, updating and categorizing …

[HTML][HTML] ISTH guidelines for the diagnosis of thrombotic thrombocytopenic purpura

XL Zheng, SK Vesely, SR Cataland, P Coppo… - Journal of Thrombosis …, 2020 - Elsevier
Background Despite an increase in our understandings of pathogenesis of thrombotic
thrombocytopenic purpura (TTP), the approaches for initial diagnosis and management of …

Caplacizumab treatment for acquired thrombotic thrombocytopenic purpura

M Scully, SR Cataland, F Peyvandi… - … England Journal of …, 2019 - Mass Medical Soc
Background In acquired thrombotic thrombocytopenic purpura (TTP), an immune-mediated
deficiency of the von Willebrand factor–cleaving protease ADAMTS13 allows unrestrained …

Haemolytic uraemic syndrome

F Fakhouri, J Zuber, V Frémeaux-Bacchi, C Loirat - The Lancet, 2017 - thelancet.com
Haemolytic uraemic syndrome is a form of thrombotic microangiopathy affecting
predominantly the kidney and characterised by a triad of thrombocytopenia, mechanical …

A regimen with caplacizumab, immunosuppression, and plasma exchange prevents unfavorable outcomes in immune-mediated TTP

P Coppo, M Bubenheim, E Azoulay… - Blood, The Journal …, 2021 - ashpublications.org
The anti–von Willebrand factor nanobody caplacizumab was licensed for adults with
immune-mediated thrombotic thrombocytopenic purpura (iTTP) based on prospective …

Derivation and external validation of the PLASMIC score for rapid assessment of adults with thrombotic microangiopathies: a cohort study

PK Bendapudi, S Hurwitz, A Fry, MB Marques… - The Lancet …, 2017 - thelancet.com
Background Among the syndromes characterised by thrombotic microangiopathy,
thrombotic thrombocytopenic purpura is distinguished by a severe deficiency in the …

Shiga toxin-associated hemolytic uremic syndrome: A narrative review

A Joseph, A Cointe, P Mariani Kurkdjian, C Rafat… - Toxins, 2020 - mdpi.com
The severity of human infection by one of the many Shiga toxin-producing Escherichia coli
(STEC) is determined by a number of factors: the bacterial genome, the capacity of human …

Management of thrombotic microangiopathy in pregnancy and postpartum: report from an international working group

F Fakhouri, M Scully, F Provôt, M Blasco… - Blood, The Journal …, 2020 - ashpublications.org
Pregnancy and postpartum are high-risk periods for different forms of thrombotic
microangiopathy (TMA). However, the management of pregnancy-associated TMA remains …