Restoration of flow in the aorta: a novel therapeutic target in aortic valve intervention

P Garg, M Markl, J Sathananthan, SL Sellers… - Nature Reviews …, 2024 - nature.com
Aortic blood flow patterns are closely linked to the morphology and function of the left
ventricle, aortic valve and aorta. These flow patterns demonstrate the exceptional …

Viscous energy loss in the presence of abnormal aortic flow

AJ Barker, P Van Ooij, K Bandi, J Garcia… - Magnetic resonance …, 2014 - Wiley Online Library
Purpose To present a theoretical basis for noninvasively characterizing in vivo fluid‐
mechanical energy losses and to apply it in a pilot study of patients known to express …

Experimental measurement of dynamic fluid shear stress on the aortic surface of the aortic valve leaflet

CH Yap, N Saikrishnan, G Tamilselvan… - … and modeling in …, 2012 - Springer
Aortic valve (AV) calcification is a highly prevalent disease with serious impact on mortality
and morbidity. Although exact causes and mechanisms of AV calcification are unclear …

[HTML][HTML] Analysis of turbulence effects in a patient-specific aorta with aortic valve stenosis

EL Manchester, S Pirola, MY Salmasi… - Cardiovascular …, 2021 - Springer
Blood flow in the aorta is often assumed laminar, however aortic valve pathologies may
induce transition to turbulence and our understanding of turbulence effects is incomplete …

Experimental measurement of dynamic fluid shear stress on the ventricular surface of the aortic valve leaflet

CH Yap, N Saikrishnan, AP Yoganathan - Biomechanics and modeling in …, 2012 - Springer
Aortic valve (AV) calcification is a highly prevalent disease with serious impact on mortality
and morbidity. The exact causes and mechanisms of AV calcification are unclear, although …

Spatiotemporal complexity of the aortic sinus vortex

B Moore, LP Dasi - Experiments in fluids, 2014 - Springer
The aortic sinus vortex is a classical flow structure of significant importance to aortic valve
dynamics and the initiation and progression of calcific aortic valve disease. We characterize …

Modeling of unsteady non-Newtonian blood flow through a stenosed artery: with nanoparticles

A Zaman, AA Khan, N Ali - Journal of the Brazilian Society of Mechanical …, 2018 - Springer
Literature survey related to the nanoparticles reveals that nanofluids are getting popularity in
hematological treatment. Development in this direction motivated us to write a theoretical …

On the significance of systolic flow waveform on aortic valve energy loss

H Hatoum, BL Moore, LP Dasi - Annals of biomedical engineering, 2018 - Springer
This study aims to quantitatively and qualitatively assess energy dissipation in the aortic
valve as a function of systolic aortic flow waveform representing pathologies where flow time …

Numerical simulation of time-dependent non-Newtonian nanopharmacodynamic transport phenomena in a tapered overlapping stenosed artery

N Ali, A Zaman, M Sajid, OA Bég… - … and Technology: An …, 2018 - dl.begellhouse.com
Nanofluids are becoming increasingly popular in novel hematological treatments and in
advanced nanoscale biomedical devices. Motivated by recent developments in this area, a …

Flow characteristics around a deformable stenosis under pulsatile flow condition

W Choi, JH Park, H Byeon, SJ Lee - Physics of Fluids, 2018 - pubs.aip.org
A specific portion of a vulnerable stenosis is deformed periodically under a pulsatile blood
flow condition. Detailed analysis of such deformable stenosis is important because stenotic …