The deleterious consequences of snake envenomation are due to the extreme protein
complexity of snake venoms. Therefore, the identification of their components is crucial for …

Background The treatment for snakebites is early administration of antivenom, which can be
highly effective in inhibiting the systemic effects of snake venoms, but is less effective in the …

Hemostasis is a complex set of biological processes responsible for blood fluidity within
normal vessels and for the physiological interruption of bleeding in cases of vascular injury …

Previous studies have demonstrated the potential antiophidic activity of Zanthoxylum
monogynum A. St.-Hil. a tree from the Rutaceae family native to South America. In this …

Background: Snake venoms are composed of pharmacologically active proteins that are
evolutionarily diverse, stable and specific to targets. Hence, venoms have been explored as …

Abstract Phospholipases A 2 (PLA 2 s) are found in almost every venomous snake family. In
snakebites, some PLA 2 s can quickly cause local myonecrosis, which may lead to …

Proteins isolated from natural sources can be composed of a mixture of isoforms with similar
physicochemical properties that coexist in the final steps of purification. Yet, even where …

BmooMPα-I has kininogenase activity, cleaving kininogen releasing bradykinin and can
hydrolyze angiotensin I at post-proline and aspartic acid positions, generating an inactive …

BmooMPα-I has kininogenase activity, cleaving kininogen releasing bradykinin and can
hydrolyze angiotensin I at post-proline and aspartic acid positions, generating an inactive …

Phage Display (PD) technique is widely used for drug discovery and development. One of its
great applications is to improve immunological studies. The objective of this work was to …