Tablets are the most widely utilized solid oral dosage forms because of the advantages of
self-administration, stability, ease of handling, transportation, and good patient compliance …

Ingestible sensor systems are unique tools for obtaining physiological data from an
undisturbed gastrointestinal tract. Since their dimensions correspond to monolithic oral …

Real-time monitoring of the gastrointestinal tract in a safe and comfortable manner is
valuable for the diagnosis and therapy of many diseases. Within this realm, our review …

Abstract Model-informed drug discovery and development (MID3) shows great advantages
in facilitating drug development. A physiologically based pharmacokinetic model is one of …

Oral dosage forms are the most widely and frequently used formulations to deliver active
pharmaceutical ingredients (APIs), due to their ease of administration and noninvasiveness …

An emerging concern globally, particularly in developed countries, is the rising prevalence
of Inflammatory Bowel Diseases (IBDs), such as Crohn's disease. Oral delivery technologies …

Physiologically based pharmacokinetic/pharmacodynamic (PBPK/PD) modeling has been
extensively applied to quantitatively translate in vitro data, predict the in vivo performance …

The purpose of the present study was to study tablet disintegration by direct visualization, in
vivo and in vitro. Based on literature data, a standard conventional paracetamol (CP) tablet …

OBJECTIVE To evaluate the effects of housing environment on oral absorption of
acetaminophen in dogs. ANIMALS 6 healthy Beagles. PROCEDURES Acetaminophen (325 …