[HTML][HTML] Diagnosis and management of primary biliary cholangitis

ZM Younossi, D Bernstein, ML Shiffman… - Official journal of the …, 2019 - journals.lww.com
Primary biliary cholangitis (PBC) is a chronic, cholestatic, autoimmune disease with a
variable progressive course. PBC can cause debilitating symptoms including fatigue and …

[PDF][PDF] Primary biliary cholangitis: 2018 practice guidance from the American Association for the Study of Liver Diseases

KD Lindor, CL Bowlus, J Boyer, C Levy, M Mayo - Hepatology, 2019 - Wiley Online Library
This American Association for the Study of Liver Diseases (AASLD) 2018 Practice Guidance
on Primary Biliary Cholangitis (PBC) is an update of the PBC guidelines published in 2009 …

EASL Clinical Practice Guidelines: The diagnosis and management of patients with primary biliary cholangitis

GM Hirschfield, U Beuers, C Corpechot, P Invernizzi… - Journal of …, 2017 - Elsevier
Primary biliary cholangitis (PBC) is a chronic inflammatory autoimmune cholestatic liver
disease, which when untreated will culminate in end-stage biliary cirrhosis. Diagnosis is …

The British Society of Gastroenterology/UK-PBC primary biliary cholangitis treatment and management guidelines

GM Hirschfield, JK Dyson, GJM Alexander… - Gut, 2018 - gut.bmj.com
Primary biliary cholangitis (formerly known as primary biliary cirrhosis, PBC) is an
autoimmune liver disease in which a cycle of immune mediated biliary epithelial cell injury …

Development and validation of a scoring system to predict outcomes of patients with primary biliary cirrhosis receiving ursodeoxycholic acid therapy

WJ Lammers, GM Hirschfield, C Corpechot, F Nevens… - Gastroenterology, 2015 - Elsevier
Background & Aims Approaches to risk stratification for patients with primary biliary cirrhosis
(PBC) are limited, single-center based, and often dichotomous. We aimed to develop and …

[PDF][PDF] The UK‐PBC risk scores: derivation and validation of a scoring system for long‐term prediction of end‐stage liver disease in primary biliary cholangitis

M Carbone, SJ Sharp, S Flack, D Paximadas… - …, 2016 - Wiley Online Library
The biochemical response to ursodeoxycholic acid (UDCA)—so‐called “treatment
response”—strongly predicts long‐term outcome in primary biliary cholangitis (PBC) …

[PDF][PDF] Risk stratification in autoimmune cholestatic liver diseases: opportunities for clinicians and trialists

PJ Trivedi, C Corpechot, A Pares, GM Hirschfield - Hepatology, 2016 - Wiley Online Library
Primary biliary cirrhosis (PBC) and primary sclerosing cholangitis (PSC) are infrequent
autoimmune cholestatic liver diseases, that disproportionate to their incidence and …

Goals of treatment for improved survival in primary biliary cholangitis: treatment target should be bilirubin within the normal range and normalization of alkaline …

CFM Perez, MH Harms, KD Lindor… - Official journal of the …, 2020 - journals.lww.com
METHODS: The patient cohort from the GLOBAL PBC Study Group was used, comprising of
long-term follow-up data from European and North American centers. Ursodeoxycholic acid …

Stratification of hepatocellular carcinoma risk in primary biliary cirrhosis: a multicentre international study

PJ Trivedi, WJ Lammers, HR Van Buuren, A Parés… - Gut, 2016 - gut.bmj.com
Objective Hepatocellular carcinoma (HCC) is an infrequent yet critical event in primary
biliary cirrhosis (PBC); however, predictive tools remain ill-defined. Our objective was to …

Effects of bezafibrate on outcome and pruritus in primary biliary cholangitis with suboptimal ursodeoxycholic acid response

A Reig, P Sesé, A Parés - Official journal of the American College …, 2018 - journals.lww.com
OBJECTIVES: Adding fibrates improves liver biochemistries in patients with primary biliary
cholangitis (PBC) and suboptimal response to ursodeoxycholic acid (UDCA). As there are …