Thiazole: A versatile standalone moiety contributing to the development of various drugs and biologically active agents

MF Arshad, A Alam, AA Alshammari, MB Alhazza… - Molecules, 2022 - mdpi.com
For many decades, the thiazole moiety has been an important heterocycle in the world of
chemistry. The thiazole ring consists of sulfur and nitrogen in such a fashion that the pi (π) …

Thiazole: A review on chemistry, synthesis and therapeutic importance of its derivatives

M T. Chhabria, S Patel, P Modi… - Current topics in …, 2016 - benthamdirect.com
Thiazole, a unique heterocycle containing sulphur and nitrogen atoms, occupies an
important place in medicinal chemistry. It is an essential core scaffold present in many …

[HTML][HTML] Treatment modalities and evaluation models for periodontitis

M Tariq, Z Iqbal, J Ali, S Baboota… - International journal …, 2012 - ncbi.nlm.nih.gov
Periodontitis is the most common localized dental inflammatory disease related with several
pathological conditions like inflammation of gums (gingivitis), degeneration of periodontal …

Development and evaluation of biodegradable chitosan films of metronidazole and levofloxacin for the management of periodontitis

G Khan, SK Yadav, RR Patel, G Nath, M Bansal… - Aaps Pharmscitech, 2016 - Springer
Metronidazole (MZ) and levofloxacin (LF) are widely employed for treatment of periodontitis,
but high oral dose and resistance development after long-term oral administration limit their …

Extraction and characterization of cashew tree (Anacardium occidentale) gum; use in aceclofenac dental pastes

MS Hasnain, P Rishishwar, S Rishishwar, S Ali… - International journal of …, 2018 - Elsevier
In the current work, the usefulness of extracted cashew tree gum (CG) as pharmaceutical
excipient in dental pastes containing aceclofenac (AC) for the pain management in the …

Micromatricial metronidazole benzoate film as a local mucoadhesive delivery system for treatment of periodontal diseases

AH El-Kamel, LY Ashri, IA Alsarra - AAPS pharmscitech, 2007 - Springer
The main objective of this study was to develop a local, oral mucoadhesive metronidazole
benzoate (MET) delivery system that can be applied and removed by the patient for the …

Hydroxyapatite composites for dentistry

S Mazumder, AK Nayak, TJ Ara, MS Hasnain - … of Nanocomposite Materials …, 2019 - Elsevier
Hydroxyapatite is one of the most widely investigated bioceramic materials. Recently,
several hydroxyapatite composites have been developed for various biomedical uses …

An injectable in situ gel with cubic and hexagonal nanostructures for local treatment of chronic periodontitis

L Mei, X Huang, Y Xie, J Chen, Y Huang, B Wang… - Drug …, 2017 - Taylor & Francis
Periodontitis is a chronic bacterial infection, and its effective treatment is dependent on the
retention of antibiotics of effective concentrations at the periodontal pockets. In this study, a …

Innovative coenzyme Q10-loaded nanoformulation as an adjunct approach for the management of moderate periodontitis: preparation, evaluation, and clinical study

MA Shaheen, SH Elmeadawy, FB Bazeed… - Drug delivery and …, 2020 - Springer
Periodontal diseases are worldwide chronic inflammatory conditions that are associated
with heavy production of reactive oxygen species followed by damage of the tooth …

[HTML][HTML] Evaluation of metronidazole nanofibers in patients with chronic periodontitis: A clinical study

TP Chaturvedi, R Srivastava… - International journal …, 2012 - ncbi.nlm.nih.gov
Aim: Prevention of periodontal disease progression is the primary goal of periodontal
therapy. When conventional therapy is found to be inadequate in achieving periodontal …