At least 20 different chromosomal regions have been linked to type 1 diabetes (T1D)
susceptibility in humans, using genome screening, candidate gene testing, and studies of …

The authors performed a meta-analysis of 33 studies examining the association of type 1
diabetes mellitus with polymorphisms in the cytotoxic T-lymphocyte-associated antigen-4 …

During the past decade, the genetics of type 1 (insulin-dependent) diabetes mellitus (IDDM)
has been studied extensively and the disorder has become a paradigm for genetically …

Abstract Type 1 (insulin‐dependent) diabetes mellitus is strongly associated with
autoimmune phenomena connected to the loss of β‐cells in the pancreatic islets. Despite …

Aims/hypothesis: Five different types of maturity-onset diabetes of the young (MODY) have
been identified until now but mutation screening suggests that more MODY genes exist …

The contribution of the candidate gene CTLA4 to type 1 diabetes is not well established.
Although several polymorphisms have been repeatedly associated to the disease, several …

A recent study mapped the known association of type 1 diabetes with the cytotoxic T
lymphocyte-associated antigen 4 gene to a polymorphism at the 3′ end (+ 6230G> A), but …

Cytotoxic T lymphocyte-associated antigen 4 (CTLA4) is an important negative regulator of T-
cell response and its genetic association with type 1 diabetes (T1D) has recently been …

OBJECTIVE: We studied the association between type 1 diabetes with autoimmune thyroid
disease (AITD) and A/G allele polymorphism in exon 1 of the CTLA-4 gene in a Japanese …

Abstract Type-1 diabetes mellitus (T1DM) is a progressive complex autoimmune disease in
which combinations of environmental as well as genetic factors contribute to T-cell mediated …