Microbiome-based therapeutics
MT Sorbara, EG Pamer - Nature Reviews Microbiology, 2022 - nature.com
Symbiotic microorganisms inhabiting the gastrointestinal tract promote health by decreasing
susceptibility to infection and enhancing resistance to a range of diseases. In this Review …
susceptibility to infection and enhancing resistance to a range of diseases. In this Review …
[HTML][HTML] The spread of antibiotic resistance to humans and potential protection strategies
D Ding, B Wang, X Zhang, J Zhang, H Zhang… - Ecotoxicology and …, 2023 - Elsevier
Antibiotic resistance is currently one of the greatest threats to human health. Widespread
use and residues of antibiotics in humans, animals, and the environment can exert selective …
use and residues of antibiotics in humans, animals, and the environment can exert selective …
Microbiome diversity protects against pathogens by nutrient blocking
The human gut microbiome plays an important role in resisting colonization of the host by
pathogens, but we lack the ability to predict which communities will be protective. We …
pathogens, but we lack the ability to predict which communities will be protective. We …
[HTML][HTML] The lung–gut axis during viral respiratory infections: the impact of gut dysbiosis on secondary disease outcomes
V Sencio, MG Machado, F Trottein - Mucosal Immunology, 2021 - Elsevier
Bacteria that colonize the human gastrointestinal tract are essential for good health. The gut
microbiota has a critical role in pulmonary immunity and host's defense against viral …
microbiota has a critical role in pulmonary immunity and host's defense against viral …
[HTML][HTML] Mechanism of the gut microbiota colonization resistance and enteric pathogen infection
The mammalian gut microbial community, known as the gut microbiota, comprises trillions of
bacteria, which co-evolved with the host and has an important role in a variety of host …
bacteria, which co-evolved with the host and has an important role in a variety of host …
[HTML][HTML] Butyrate's role in human health and the current progress towards its clinical application to treat gastrointestinal disease
K Hodgkinson, F El Abbar, P Dobranowski… - Clinical Nutrition, 2023 - Elsevier
Butyrate is a key energy source for colonocytes and is produced by the gut microbiota
through fermentation of dietary fiber. Butyrate is a histone deacetylase inhibitor and also …
through fermentation of dietary fiber. Butyrate is a histone deacetylase inhibitor and also …
Gut microbiota and colonization resistance against bacterial enteric infection
QR Ducarmon, RD Zwittink, BVH Hornung… - Microbiology and …, 2019 - Am Soc Microbiol
The gut microbiome is critical in providing resistance against colonization by exogenous
microorganisms. The mechanisms via which the gut microbiota provide colonization …
microorganisms. The mechanisms via which the gut microbiota provide colonization …
[HTML][HTML] Immunological mechanisms of inflammatory diseases caused by gut microbiota dysbiosis: A review
J Chu, S Feng, C Guo, B Xue, K He, L Li - Biomedicine & …, 2023 - Elsevier
The gut microbiota is indispensable for maintaining host health by enhancing the host's
digestive capacity, safeguarding the intestinal epithelial barrier, and preventing pathogen …
digestive capacity, safeguarding the intestinal epithelial barrier, and preventing pathogen …
The role of the microbiota in infectious diseases
J Libertucci, VB Young - Nature microbiology, 2019 - nature.com
The human body is colonized by a diverse community of microorganisms collectively
referred to as the microbiota. Here, we describe how the human microbiota influences …
referred to as the microbiota. Here, we describe how the human microbiota influences …
Biological function of short-chain fatty acids and its regulation on intestinal health of poultry
L Liu, Q Li, Y Yang, A Guo - Frontiers in Veterinary Science, 2021 - frontiersin.org
Short-chain fatty acids (SCFAs) are metabolites generated by bacterial fermentation of
dietary fiber (DF) in the hindgut. SCFAs are mainly composed of acetate, propionate and …
dietary fiber (DF) in the hindgut. SCFAs are mainly composed of acetate, propionate and …