Chiral stationary phases for liquid chromatography: recent developments

J Teixeira, ME Tiritan, MMM Pinto, C Fernandes - Molecules, 2019 - mdpi.com
The planning and development of new chiral stationary phases (CSPs) for liquid
chromatography (LC) are considered as continuous and evolutionary issues since the …

[HTML][HTML] Recent developments in the high-throughput separation of biologically active chiral compounds via high performance liquid chromatography

C De Luca, S Felletti, FA Franchina, D Bozza… - … of Pharmaceutical and …, 2024 - Elsevier
Bioactive compounds, including active pharmaceutical ingredients (APIs), are often chiral
molecules where stereoisomers have different biological and therapeutic activity …

Advances and innovations in liquid chromatography stationary phase supports

K Broeckhoven, G Desmet - Analytical Chemistry, 2020 - ACS Publications
The continuous evolution of stationary phase supports over the past decades have allowed
a vast increase the separation performance in liquid chromatography. As in any …

Understanding the transition from high-selective to high-efficient chiral separations by changing the organic modifier with zwitterionic-teicoplanin chiral stationary …

S Felletti, C De Luca, G Mazzoccanti… - Analytical …, 2023 - ACS Publications
The retention behavior of small molecules and N-protected amino acids on a zwitterionic
teicoplanin chiral stationary phase (CSP), prepared on superficially porous particles (SPPs) …

Chromatographic supports for enantioselective liquid chromatography: Evolution and innovative trends

C Fernandes, R Lima, MMM Pinto, ME Tiritan - Journal of Chromatography …, 2022 - Elsevier
Diverse approaches have been explored as chromatographic supports for chiral stationary
phases (CSPs) in liquid chromatography (LC), such as the introduction of nanoparticles …

High-throughput and ultrafast liquid chromatography

AS Kaplitz, GA Kresge, B Selover, L Horvat… - Analytical …, 2019 - ACS Publications
Analytical scientists working in many sectors have long expressed the need for increasingly
fast chromatographic separations. The pharmaceutical industry, for example, has a growing …

Shedding light on mechanisms leading to convex-upward van Deemter curves on a cellulose tris (4-chloro-3-methylphenylcarbamate)-based chiral stationary phase

S Felletti, C De Luca, G Lievore, T Chenet… - … of Chromatography A, 2020 - Elsevier
An unusual convex-upward van Deemter curve was observed for the more retained
enantiomer of a chiral sulfoxide (2-(benzylsulfinyl) benzamide) on a cellulose tris (4-chloro-3 …

Investigation of retention behavior of natural cannabinoids on differently substituted polysaccharide-based chiral stationary phases under reversed-phase liquid …

C De Luca, A Buratti, W Umstead, P Franco… - … of Chromatography A, 2022 - Elsevier
The growing popularity of cannabis products and recent legalization of cannabis for
recreational purposes have contributed to the increase of the demand for analytical methods …

Investigating the effect of polarity of stationary and mobile phases on retention of cannabinoids in normal phase liquid chromatography

C De Luca, A Buratti, Y Krauke, S Stephan… - Analytical and …, 2022 - Springer
This work reports about a screening of four adsorbents with different polarity employed for
the separation of the main phytocannabinoids contained in Cannabis sativa L., under …

Strong cation-and zwitterion-exchange-type mixed-mode stationary phases for separation of pharmaceuticals and biogenic amines in different chromatographic …

D Wolrab, P Frühauf, N Kolderová, M Kohout - Journal of Chromatography …, 2021 - Elsevier
A set of new mixed-mode ion-exchange stationary phases is presented. The backbone of
organic selectors is formed by a linear hydrocarbon chain, which is divided into two parts of …