The mechanism of DNA methylation and miRNA in breast cancer

L Ma, C Li, H Yin, J Huang, S Yu, J Zhao… - International Journal of …, 2023 - mdpi.com
Breast cancer is the most prevalent cancer in the world. Currently, the main treatments for
breast cancer are radiotherapy, chemotherapy, targeted therapy and surgery. The treatment …

[HTML][HTML] DNMT3A and DNMT3B in breast tumorigenesis and potential therapy

X Man, Q Li, B Wang, H Zhang, S Zhang… - Frontiers in cell and …, 2022 - frontiersin.org
Breast cancer has become a leading cause of cancer-related deaths in women worldwide.
DNA methylation has been revealed to play an enormously important role in the …

Crosstalk between methylation and ncRNAs in breast cancer: therapeutic and diagnostic implications

Y Liu, P Leng, Y Liu, J Guo, H Zhou - International Journal of Molecular …, 2022 - mdpi.com
Breast cancer, as a highly heterogeneous malignant tumor, is one of the primary causes of
death among females worldwide. The etiology of breast cancer involves aberrant epigenetic …

From molecular pathogenesis to therapy: Unraveling non-coding RNAs/DNMT3A axis in human cancers

C Huang, SM Aghaei-Zarch - Biochemical Pharmacology, 2024 - Elsevier
Cancer is a comprehensive classification encompassing more than 100 forms of
malignancies that manifest in diverse tissues within the human body. Recent studies have …

miR-142-3p improves paclitaxel sensitivity in resistant breast cancer by inhibiting autophagy through the GNB2-AKT-mTOR pathway

Y Shi, J Wang, S Tao, S Zhang, L Mao, X Shi, W Wang… - Cellular …, 2023 - Elsevier
Breast cancer has overtaken lung cancer as the most prevalent cancer worldwide. The
development of advanced drug resistance inhibits the efficacy of paclitaxel (PTX) as a first …

miRNAs in the prognosis of triple-negative breast cancer: A review

KV Anilkumar, LP Rema, MC John, TV John, A George - Life Sciences, 2023 - Elsevier
Abstract Triple-Negative Breast Cancer (TNBC) is a highly aggressive and invasive type of
breast cancer (BC) with high mortality rate wherein effective target medicaments are lacking …

Emerging roles of interactions between ncRNAs and other epigenetic modifications in breast cancer

J Xie, L Gan, B Xue, X Wang, X Pei - Frontiers in Oncology, 2023 - frontiersin.org
Up till the present moment, breast cancer is still the leading cause of cancer-related death in
women worldwide. Although the treatment methods and protocols for breast cancer are …

The mechanism of action of Fangji Huangqi Decoction on epithelial-mesenchymal transition in breast cancer using high-throughput next-generation sequencing and …

Q Guo, X Pei, A Chu, Y Guo, Y Fan, C Wang… - Journal of …, 2022 - Elsevier
Abstract Ethnopharmacological relevance Fangji Huangqi Decoction (FHD) is widely used
in traditional Chinese medicine (TCM). FHD has been hypothesized to inhibit the epithelial …

Non-coding RNAs in EMT regulation: association with tumor progression and therapy response

M Sadrkhanloo, M Entezari, M Rashidi… - European Journal of …, 2022 - Elsevier
RNA molecules lacking capacity in protein translation, are known as non-coding RNAs
(ncRNAs). Growth, differentiation and migration are influenced by ncRNAs in cells. The …

Potential epigenetic modifications implicated in triple-to quadruple-negative breast cancer transition: a review

A Muhammad, GE Forcados, BS Katsayal, RS Bako… - …, 2022 - Taylor & Francis
Current research on triple-negative breast cancer (TNBC) has resulted in delineation into
the quadruple-negative breast cancer (QNBC) subgroup. Epigenetic modifications such as …