[HTML][HTML] Unraveling Biomarker Signatures in Triple-Negative Breast Cancer: A Systematic Review for Targeted Approaches

P Pastena, H Perera, A Martinino, W Kartsonis… - International Journal of …, 2024 - mdpi.com
Triple-negative breast cancer (TNBC) is one of the most aggressive subtypes of breast
cancer, marked by poor outcomes and dismal prognosis. Due to the absence of targetable …

Tumor microenvironment: A niche for cancer stem cell immunotherapy

MC Borlongan, D Saha, H Wang - Stem Cell Reviews and Reports, 2024 - Springer
Abstract Tumorigenic Cancer Stem Cells (CSCs), often called tumor-initiating cells (TICs),
represent a unique subset of cells within the tumor milieu. They stand apart from the bulk of …

Glutamine transporter SLC38A3 promotes breast cancer metastasis via Gsk3β/β-catenin/EMT pathway

Z Tan, K Boyapati, CM Tressler, NM Jenkinson… - Cancer Letters, 2024 - Elsevier
Breast cancer is the leading cancer-related cause of death in women. Here we show that
solute carrier family 38-member 3 (SLC38A3) is overexpressed in breast cancer, particularly …

[HTML][HTML] Cancer-associated fibroblasts and their role in tumor progression

MS Ermakov, AA Nushtaeva, VA Richter… - Vavilov Journal of …, 2022 - ncbi.nlm.nih.gov
The stromal elements of a malignant tumor can promote cancer progression and metastasis.
The structure of the tumor stroma includes connective tissue elements, blood vessels …

[HTML][HTML] Stem cells and cancer stem cells: the Jekyll and Hyde scenario and their implications in stem cell therapy

WS Wan Kamarul Zaman, AA Nurul, F Nordin - Biomedicines, 2021 - mdpi.com
“Jekyll and Hyde” refers to persons with an unpredictably dual personality, who are battling
between good and evil within themselves In this regard, even cells consist of good and evil …

[HTML][HTML] Prognostic value of Maspin protein level in patients with triple negative breast cancer

RG do Nascimento, MPF da Conceição… - Scientific Reports, 2024 - nature.com
The search for prognostic markers in breast cancer has bumped into a typical feature of
these tumors, intra and intertumoral heterogeneity. Changes in the expression profile …

[HTML][HTML] The expression pattern of surface markers in canine adipose-derived mesenchymal stem cells

N Krešić, M Prišlin, D Vlahović, P Kostešić… - International journal of …, 2021 - mdpi.com
The influence of cultivation on the expression pattern of canine adipose-derived
mesenchymal stem cells (cAD-MSCs) surface markers, contributing to, among others, the …

[HTML][HTML] Linc‑OIP5 loss regulates migration and invasion in MDA‑MB‑231 breast cancer cells by inhibiting YAP1/JAG1 signaling

Q Zhu, Y Li, X Dong, Y Yang, H Wang… - Oncology …, 2020 - spandidos-publications.com
Breast cancer is the most prevalent cancer among women, and diagnosis and treatment
represent a substantial challenge due to the lack of adequate molecular targets. It has been …

[HTML][HTML] Evidence of a synthetic lethality interaction between SETDB1 histone methyltransferase and CHD4 chromatin remodeling protein in a triple negative breast …

MS Moraes-Almeida, MC Sogayar… - Brazilian Journal of …, 2023 - SciELO Brasil
During the tumorigenic process, cancer cells may become overly dependent on the activity
of backup cellular pathways for their survival, representing vulnerabilities that could be …

Intricate relationship between cancer stemness, metastasis, and drug resistance

TC Dakal, R Bhushan, C Xu, BR Gadi… - MedComm, 2024 - Wiley Online Library
Cancer stem cells (CSCs) are widely acknowledged as the drivers of tumor initiation,
epithelial‐mesenchymal transition (EMT) progression, and metastasis. Originating from both …