From mesenchymal stromal/stem cells to insulin-producing cells: progress and challenges
MA Ghoneim, AF Refaie, BL Elbassiouny… - Stem Cell Reviews and …, 2020 - Springer
Mesenchymal stromal cells (MSCs) are an attractive option for cell therapy for type 1
diabetes mellitus (DM). These cells can be obtained from many sources, but bone marrow …
diabetes mellitus (DM). These cells can be obtained from many sources, but bone marrow …
Current status of stem cell therapy for type 1 diabetes: a critique and a prospective consideration
Over the past decade, there had been progress in the development of cell therapy for insulin-
dependent diabetes. Nevertheless, important hurdles that need to be overcome still remain …
dependent diabetes. Nevertheless, important hurdles that need to be overcome still remain …
[HTML][HTML] Effectiveness and safety of human umbilical cord-mesenchymal stem cells for treating type 2 diabetes mellitus
XF Lian, DH Lu, HL Liu, YJ Liu, XQ Han… - World Journal of …, 2022 - ncbi.nlm.nih.gov
BACKGROUND Progressive pancreatic β-cell dysfunction is a fundamental part of the
pathology of type 2 diabetes mellitus (T2DM). Cellular therapies offer novel opportunities for …
pathology of type 2 diabetes mellitus (T2DM). Cellular therapies offer novel opportunities for …
Mesenchymal stem cell therapy in diabetic cardiomyopathy
JS da Silva, RGJ Gonçalves, JF Vasques, BS Rocha… - Cells, 2022 - mdpi.com
The incidence and prevalence of diabetes mellitus (DM) are increasing worldwide, and the
resulting cardiac complications are the leading cause of death. Among these complications …
resulting cardiac complications are the leading cause of death. Among these complications …
Mesenchymal stem cells: an excellent candidate for the treatment of diabetes mellitus
Q Huang, Y Huang, J Liu - International Journal of …, 2021 - Wiley Online Library
Mesenchymal stem cells (MSCs) are adult stem cells (ASCs) known for repairing damaged
cells, exerting anti‐inflammatory responses and producing immunoregulatory effects that …
cells, exerting anti‐inflammatory responses and producing immunoregulatory effects that …
Efficacy of mesenchymal stem cell therapy on glucose levels in type 2 diabetes mellitus: A systematic review and meta‐analysis
H Ranjbaran, B Mohammadi Jobani… - Journal of Diabetes …, 2021 - Wiley Online Library
Abstract Aims/Introduction In recent years, mesenchymal cellular therapies have received
much attention in the treatment of diabetes. In this meta‐analysis, we aimed to evaluate the …
much attention in the treatment of diabetes. In this meta‐analysis, we aimed to evaluate the …
Tissue engineering approaches and generation of insulin-producing cells to treat type 1 diabetes
M Khazaei, F Khazaei, E Niromand… - Journal of drug …, 2023 - Taylor & Francis
Tissue engineering (TE) has become a new effective solution to a variety of medical
problems, including diabetes. Mesenchymal stem cells (MSCs), which have the ability to …
problems, including diabetes. Mesenchymal stem cells (MSCs), which have the ability to …
Application of mesenchymal stem cells derived from the umbilical cord or Wharton's jelly and their extracellular vesicles in the treatment of various diseases
Mesenchymal stem cells (MSCs) originating from the umbilical cord (UC) or Wharton's jelly
(WJ) have attracted substantial interest due to their potential to augment therapeutic …
(WJ) have attracted substantial interest due to their potential to augment therapeutic …
Autophagy enhances the differentiation of insulin-producing cells from Wharton's jelly-derived mesenchymal stem cells
N Azarbarz, F Nejaddehbashi, L Khorsandi, DB Nejad… - Tissue and Cell, 2024 - Elsevier
Autophagy disruption suppresses insulin production and induces diabetes. The role of
autophagy in the differentiation of Wharton's jelly (WJ)-derived mesenchymal stem cells …
autophagy in the differentiation of Wharton's jelly (WJ)-derived mesenchymal stem cells …
Perinatal Stem Cell Therapy to Treat Type 1 Diabetes Mellitus: A Never-Say-Die Story of Differentiation and Immunomodulation
F Paris, V Pizzuti, P Marrazzo, A Pession… - International Journal of …, 2022 - mdpi.com
Human term placenta and other postpartum-derived biological tissues are promising
sources of perinatal cells with unique stem cell properties. Among the massive current …
sources of perinatal cells with unique stem cell properties. Among the massive current …