Abstract Background Zinc (Zn) has a diverse role in many biological processes, such as
growth, immunity, anti-oxidation system, homeostatic, and repairing. It acts as a regulatory …

Non-apoptotic forms of programmed cell death are targets for novel approaches in
anticancer therapy. Indeed, cancer cells often present with mutations in the apoptotic …

Reports implicating microglia-derived nerve growth factor (NGF) during programmed cell
death in the developing chick retina led us to investigate its possible role in degenerative …

Nerve growth factor (NGF) is critical for the development and maintenance of sympathetic
and sensory neurons in the developing nervous system, including nociceptors. In the adult …

Zinc levels are high in ocular tissues and the distribution is non-uniform. Zinc is particularly
concentrated in the corneal epithelium and posterior stroma. Zinc is the most abundant trace …

Nerve growth factor (NGF) is a protein necessary for development and maintenance of the
sympathetic and sensory nervous systems. We have previously shown that the NGF N …

There is a significant overlap between brain areas with Zn2+ and Cu2+ pathological dys‐
homeostasis and those in which the nerve growth factor (NGF) performs its biological role …

Cumulative evidence indicates that activation of cyclin D-dependent kinase 4/6 (cdk4/6)
represents a major trigger of cell cycle reentry and apoptosis in vertebrate neurons. We …

Zinc has been known for many years to inhibit apoptosis but the mechanism remains
unclear. Originally thought to inhibit an apoptotic endonuclease, zinc has subsequently …

Some metal ions of the d-block are necessary for the proper growth, functioning and
maintenance of the central nervous system. In particular, copper and zinc ions have …