The globally increasing prevalence of obesity is associated with the development of
metabolic diseases such as type 2 diabetes, dyslipidemia, and fatty liver. Excess adipose …

Obesity is one of the biggest public health concerns identified by an increase in adipose
tissue mass as a result of adipocyte hypertrophy and hyperplasia. Pertaining to the …

Simple Summary Progress in adipose research has shifted our understanding of adipose
tissue from being a homogenous, quiescent depot for energy storage to a highly dynamic …

Adipose tissue (AT) expands through both hyperplasia and hypertrophy. During
adipogenesis, adipose stromal and progenitor cells (ASPCs) proliferate and then …

In this review, we delve into the intricate relationship between white adipose tissue (WAT)
remodeling and metabolic aspects in obesity, with a specific focus on individuals with …

Obesity-associated type 2 diabetes (DM) leads to adipose tissue dysfunction. Lumican is a
proteoglycan implicated in obesity, insulin resistance (IR), and adipocyte dysfunction. Using …

Brown adipose tissue (BAT) is a key thermogenic organ whose expression of uncoupling
protein 1 (UCP1) and ability to maintain body temperature in response to acute cold …

Aims Chronic inflammation plays crucial roles in obesity-induced metabolic diseases.
Protein tyrosine phosphatase receptor type O (PTPRO) is a member of the R3 subfamily of …

Purpose Limited studies have shown positive and negative associations of serum amylase
A1 (SAA1) gene in childhood obesity, previously showed the relation with obesity in different …

Alterations of the extracellular matrix contribute to adipose tissue dysfunction in metabolic
disease. We studied the role of matrix density in regulating human adipocyte phenotype in a …