The LUCA and its complex virome

M Krupovic, VV Dolja, EV Koonin - Nature Reviews Microbiology, 2020 - nature.com
The last universal cellular ancestor (LUCA) is the most recent population of organisms from
which all cellular life on Earth descends. The reconstruction of the genome and phenotype …

The Syntrophy hypothesis for the origin of eukaryotes revisited

P López-García, D Moreira - Nature microbiology, 2020 - nature.com
The discovery of Asgard archaea, phylogenetically closer to eukaryotes than other archaea,
together with improved knowledge of microbial ecology, impose new constraints on …

Isolation of an archaeon at the prokaryote–eukaryote interface

H Imachi, MK Nobu, N Nakahara, Y Morono… - Nature, 2020 - nature.com
The origin of eukaryotes remains unclear,,–. Current data suggest that eukaryotes may have
emerged from an archaeal lineage known as 'Asgard'archaea,. Despite the eukaryote-like …

Promotion of protocell self-assembly from mixed amphiphiles at the origin of life

SF Jordan, H Rammu, IN Zheludev… - Nature ecology & …, 2019 - nature.com
Vesicles formed from single-chain amphiphiles (SCAs) such as fatty acids probably played
an important role in the origin of life. A major criticism of the hypothesis that life arose in an …

[HTML][HTML] Role of the lipid bilayer in outer membrane protein folding in Gram-negative bacteria

JE Horne, DJ Brockwell, SE Radford - Journal of Biological Chemistry, 2020 - ASBMB
β-Barrel outer membrane proteins (OMPs) represent the major proteinaceous component of
the outer membrane (OM) of Gram-negative bacteria. These proteins perform key roles in …

Proposal of the reverse flow model for the origin of the eukaryotic cell based on comparative analyses of Asgard archaeal metabolism

A Spang, CW Stairs, N Dombrowski, L Eme… - Nature …, 2019 - nature.com
The origin of eukaryotes represents an unresolved puzzle in evolutionary biology. Current
research suggests that eukaryotes evolved from a merger between a host of archaeal …

Origin and early evolution of the eukaryotic cell

T Gabaldón - Annual Review of Microbiology, 2021 - annualreviews.org
The origin of eukaryotes has been defined as the major evolutionary transition since the
origin of life itself. Most hallmark traits of eukaryotes, such as their intricate intracellular …

Self-assembly of glycerol-amphiphilic Janus dendrimers amplifies and indicates principles for the selection of stereochemistry by biological membranes

D Zhang, Q Xiao, M Rahimzadeh, M Liu… - Journal of the …, 2023 - ACS Publications
The principles for the selection of the stereochemistry of phospholipids of biological
membranes remain unclear and continue to be debated. Therefore, any new experiments on …

Bridging the membrane lipid divide: bacteria of the FCB group superphylum have the potential to synthesize archaeal ether lipids

L Villanueva, FA Bastiaan von Meijenfeldt… - The ISME …, 2021 - academic.oup.com
Archaea synthesize membranes of isoprenoid lipids that are ether-linked to glycerol-1-
phosphate (G1P), while Bacteria/Eukarya produce membranes consisting of fatty acids ester …

[HTML][HTML] Systematic comparison of unilamellar vesicles reveals that archaeal core lipid membranes are more permeable than bacterial membranes

U Łapińska, G Glover, Z Kahveci, NAT Irwin… - PLoS …, 2023 - journals.plos.org
One of the deepest branches in the tree of life separates the Archaea from the Bacteria.
These prokaryotic groups have distinct cellular systems including fundamentally different …