Functions of galectins as 'self/non-self'-recognition and effector factors

GR Vasta, C Feng, N González-Montalbán… - Pathogens and …, 2017 - academic.oup.com
Carbohydrate structures on the cell surface encode complex information that through
specific recognition by carbohydrate-binding proteins (lectins) modulates interactions …

Galectin-mediated immune recognition: Opsonic roles with contrasting outcomes in selected shrimp and bivalve mollusk species

GR Vasta, JX Wang - Developmental & Comparative Immunology, 2020 - Elsevier
Galectins are a structurally conserved family of ß-galactoside-binding lectins characterized
by a unique sequence motif in the carbohydrate recognition domain, and of wide taxonomic …

Trypanosoma cruzi extracts elicit protective immune response against chemically induced colon and mammary cancers

L Ubillos, T Freire, E Berriel… - … journal of cancer, 2016 - Wiley Online Library
Trypanosoma cruzi, the protozoan parasite that causes Chagas' disease, has anticancer
effects mediated, at least in part, by parasite‐derived products which inhibit growth of tumor …

Galectin-3 up-regulation in hypoxic and nutrient deprived microenvironments promotes cell survival

RY Ikemori, CML Machado, KM Furuzawa… - PLoS …, 2014 - journals.plos.org
Galectin-3 (gal-3) is a β-galactoside binding protein related to many tumoral aspects, eg.
angiogenesis, cell growth and motility and resistance to cell death. Evidence has shown its …

Galectins in host–pathogen interactions: structural, functional and evolutionary aspects

GR Vasta - Lectin in Host Defense Against Microbial Infections, 2020 - Springer
Galectins are a family of ß-galactoside-binding lectins characterized by a unique sequence
motif in the carbohydrate recognition domain, and evolutionary and structural conservation …

Galectin-3 accelerates the progression of oral tongue squamous cell carcinoma via a Wnt/β-catenin-dependent pathway

LP Wang, SW Chen, SM Zhuang, H Li… - Pathology & Oncology …, 2013 - Springer
The purpose of this study was to elucidate the clinicopathological significance and
mechanism of action of galectin-3 in oral tongue squamous cell carcinoma (OTSCC). Here …

Potential roles of modified pectin targeting galectin-3 against Severe Acute Respiratory Syndrome Coronavirus-2

F Odun-Ayo, L Reddy - J, 2021 - mdpi.com
Modified pectin (MP) is a bioactive complex polysaccharide that is broken down into smaller
fragments of units and used as an oral dietary supplement for cell proliferation. MP is safe …

Chemoprevention of azoxymethane-induced colonic carcinogenesis in Balb/c mice using a modified pectin alginate probiotic

F Odun-Ayo, J Mellem, T Naicker, L Reddy - Anticancer research, 2015 - ar.iiarjournals.org
Background: Increased intake of probiotic dietary fibre reduces colonic cancer risk. Modified
citrus pectin (MCP) requires optimal bioactivity to inhibit galectin-3 (GAL-3) and vascular …

Recognition of concanavalin A by cationic glucosylated liposomes

A Mauceri, S Borocci, L Galantini, L Giansanti… - Langmuir, 2014 - ACS Publications
The specificity of carbohydrate–lectin interaction has been reported as an attractive strategy
for drug delivery in cancer therapy because of the high levels of lectins in several human …

Self-assembled carbohydrate-based vesicles for lectin targeting

MC Dos Santos, YMS Micheletto, NP da Silveira… - Colloids and Surfaces B …, 2016 - Elsevier
This study examined the physicochemical interactions between vesicles formed by
phosphatidylcholine (PC) and glycosylated polymeric amphiphile N-acetyl-β-d-glucosaminyl …