Pyrido[2,3-d]pyrimidin-7(8H)-ones: Synthesis and Biomedical Applications

G Jubete, R Puig de la Bellacasa, R Estrada-Tejedor… - Molecules, 2019 - mdpi.com
Pyrido [2, 3-d] pyrimidines (1) are a type of privileged heterocyclic scaffolds capable of
providing ligands for several receptors in the body. Among such structures, our group and …

о-Aminopyrimidine Aldehydes and Ketones: Synthesis and use as Precursors to Fused Pyrimidines

AV Komkov, AА Sukhanova, LG Menchikov… - Chemistry of …, 2022 - Springer
The review summarizes literature data on the methods of synthesis of o-aminopyrimidine
aldehydes and o-aminopyrimidine ketones and their application for the construction of fused …

Design, Synthesis, and Bioevaluation of Pyrido[2,3-d]pyrimidin-7-ones as Potent SOS1 Inhibitors

M Liu, G Zhou, W Su, Y Gu, M Gao… - ACS Medicinal …, 2023 - ACS Publications
The use of small molecular modulators to target the guanine nucleotide exchange factor
SOS1 has been demonstrated to be a promising strategy for the treatment of various KRAS …

Expanding the Diversity at the C-4 Position of Pyrido[2,3-d]pyrimidin-7(8H)-ones to Achieve Biological Activity against ZAP-70

V Masip, Á Lirio, A Sánchez-López, AB Cuenca… - Pharmaceuticals, 2021 - mdpi.com
Pyrido [2, 3-d] pyrimidin-7 (8 H)-ones have attracted widespread interest due to their
similarity with nitrogenous bases found in DNA and RNA and their potential applicability as …

Six-Membered Ring Systems: Diazines and Benzo Derivatives

KA Rinderspacher - Progress in Heterocyclic Chemistry, 2020 - Elsevier
Found in natural products, and frequently used as flavoring agents or as building blocks for
pharmaceuticals, diazines and their benzo derivatives possess a diverse set of properties …

о-АМИНОПИРИМИДИНАЛЬДЕГИДЫ И КЕТОНЫ: CИНТЕЗ И ПРИМЕНЕНИЕ ДЛЯ ПОЛУЧЕНИЯ КОНДЕНСИРОВАННЫХ ПИРИМИДИНОВ

В Александр, АА Суханова, ЛГ Менчиков… - Chemistry of …, 2022 - osi131.osi.lv
В обзоре обобщены литературные данные по методам синтеза о-
аминопиримидинальдегидов и о-аминопиримидинкетонов и их применению для …

10.16-Bicyclic 6-6 Systems: Three Heteroatoms 1: 2

WA Loughlin, A Boufridi - … Heterocyclic Chemistry IV, 4th …, 2022 - research.usc.edu.au
10.16 - Bicyclic 6-6 Systems: Three Heteroatoms 1:2 - University of the Sunshine Coast,
Queensland Logo image Find research works Outputs New search Research Outputs …

[HTML][HTML] Піридо [2, 3-d] піримідин-7-они: синтез та біологічні властивості

HM Zinchenko, LV Muzychka… - Journal of Organic and …, 2019 - ophcj.nuph.edu.ua
В огляді узагальнено та систематизовано дані останніх двадцяти років щодо методів
одержання та біологічних властивостей піридо [2, 3-d] піримідин-7-онів–перспективних …