The development of increasingly efficient and cost-effective high throughput DNA
sequencing techniques has enhanced the possibility of studying complex microbial systems …

Induction of intestinal drug metabolizing enzymes can complicate the development of new
drugs, owing to the potential to cause drug-drug interactions (DDIs) leading to changes in …

A fundamental requirement for many applications in genomics is the sequencing of genetic
material (DNA/RNA). Different sequencing technologies exist, but all aim to accurately …

In recent years, the role of bioinformatics and computational biology together with omics
techniques and transcriptomics has gained tremendous importance in biomedicine and …

The NOTCH signaling pathway plays an important role in regulating various biological
processes, including lineage specification and apoptosis. Multiple components of the …

Library adaptors are short oligonucleotides that are attached to RNA and DNA samples in
preparation for next-generation sequencing (NGS). Adaptors can also include additional …

IgA nephropathy (IgAN) is a heterogeneous disease, which poses a series of challenges to
accurate diagnosis and personalized therapy. Herein, we constructed a systematic …

Abstract Background The Argentine stem weevil (ASW, Listronotus bonariensis) is a
significant pasture pest in Aotearoa New Zealand, primarily controlled by the parasitoid …

Despite intense recent research interest in archaea, the scientific community has
experienced a bottleneck in the study of genome-scale gene expression experiments by …

Precision medicine offers remarkable potential for the treatment of cancer, but is largely
focused on tumors that harbor actionable mutations. Gene expression signatures can …