Influenza A viral ribonucleoprotein (vRNP) complexes comprise the eight genomic negative-
sense RNAs, each of which is bound to multiple copies of the vRNP and a trimeric viral …

Influenza viruses are major human pathogens responsible for respiratory diseases affecting
millions of people worldwide and characterized by high morbidity and significant mortality …

The causative agent of the coronavirus disease 2019 (COVID-19) pandemic, severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), has infected millions and killed …

Viruses are obligate parasites and thus require the machinery of the host cell to replicate.
Inhibition of host factors co-opted during active infection is a strategy hosts use to suppress …

Influenza has a long history of causing morbidity and mortality in the human population
through routine seasonal spread and global pandemics. The high mutation rate of the RNA …

Influenza A NS1 and NS2 proteins are encoded by the RNA segment 8 of the viral genome.
NS1 is a multifunctional protein and a virulence factor while NS2 is involved in nuclear …

Inflammation is a pathological hallmark associated with bacterial and viral infections,
autoimmune diseases, genetic disorders, obesity and diabetes, as well as environmental …

The cell intrinsic antiviral response of multicellular organisms developed over millions of
years and critically relies on the ability to sense and eliminate viral nucleic acids. Here we …

Influenza virus has evolved replication strategies that hijack host cell pathways. To uncover
interactions between viral macromolecules and host proteins, we applied a phage display …

Avian H7 influenza viruses are recognized as potential pandemic viruses, as personnel
often become infected during poultry outbreaks. H7 infections in humans typically cause …