Coronary artery spasm-related heart failure syndrome: Literature review

MJ Hung, CT Yeh, NG Kounis, I Koniari, P Hu… - International journal of …, 2023 - mdpi.com
Although heart failure (HF) is a clinical syndrome that becomes worse over time, certain
cases can be reversed with appropriate treatments. While coronary artery spasm (CAS) is …

[HTML][HTML] Signaling Paradigms of H2S-Induced Vasodilation: A Comprehensive Review

C Munteanu, C Popescu, AI Vlădulescu-Trandafir… - Antioxidants, 2024 - mdpi.com
Hydrogen sulfide (H2S), a gas traditionally considered toxic, is now recognized as a vital
endogenous signaling molecule with a complex physiology. This comprehensive study …

Novel mouse model of myocardial infarction, plaque rupture, and stroke shows improved survival with myeloperoxidase inhibition

S Shamsuzzaman, RA Deaton, A Salamon, H Doviak… - Circulation, 2024 - ahajournals.org
BACKGROUND: Thromboembolic events, including myocardial infarction (MI) or stroke,
caused by the rupture or erosion of unstable atherosclerotic plaques are the leading cause …

[HTML][HTML] Metabolite Neu5Ac triggers SLC3A2 degradation promoting vascular endothelial ferroptosis and aggravates atherosclerosis progression in ApoE-/-mice

P Xiang, Q Chen, L Chen, J Lei, Z Yuan, H Hu, Y Lu… - Theranostics, 2023 - ncbi.nlm.nih.gov
Background: Atherosclerosis (AS) is still the major cause of cardiovascular disease (CVD)
as well as stroke. Endothelial metabolic disorder has been found to be activated and then …

TREM2 protects from atherosclerosis by limiting necrotic core formation

M Piollet, F Porsch, G Rizzo, F Kapser… - Nature cardiovascular …, 2024 - nature.com
Atherosclerosis is a chronic disease of the vascular wall driven by lipid accumulation and
inflammation in the intimal layer of arteries, and its main complications—myocardial …

Development of new genome editing tools for the treatment of hyperlipidemia

G Preta - Cells, 2023 - mdpi.com
Hyperlipidemia is a medical condition characterized by high levels of lipids in the blood. It is
often associated with an increased risk of cardiovascular diseases such as heart attacks and …

Differences in vasomotor function of mesenteric arteries between Ossabaw minipigs with predisposition to metabolic syndrome and Göttingen minipigs

C Eickelmann, HR Lieder, M Sturek… - American Journal …, 2024 - journals.physiology.org
Metabolic syndrome predisposes and contributes to the development and progression of
atherosclerosis. The minipig strain “Ossabaw” is characterized by a predisposition to …

Tanshinone IIA alleviates atherosclerosis in LDLR−/− mice by regulating efferocytosis of macrophages

J Wang, Y Zhang, X Feng, M Du, S Li… - Frontiers in …, 2023 - frontiersin.org
Background: Tanshinone IIA (TIIA) is the major lipid-soluble active ingredient of the
traditional Chinese medicine Salvia miltiorrhiza, which slows down atherosclerosis (AS) …

Contribution of the arterial cells to atherosclerosis and plaque formation

T Naiya, I Meganathan, N Ness… - American Journal …, 2024 - journals.physiology.org
Atherosclerosis is commonly known as an inflammatory disease that is characterized by lipid
deposition in the arterial wall, causing gradual restriction or complete blockade of blood …

[HTML][HTML] Chronic exposure to E-cigarette aerosols potentiates atherosclerosis in a sex-dependent manner

V Caruana, BH Giles, N Kukolj, R Juran… - Toxicology and Applied …, 2024 - Elsevier
Despite being designed for smoking cessation, e-cigarettes and their variety of flavors have
become increasingly attractive to teens and young adults. This trend has fueled concerns …