Safety in multi-assembly via paths appearing in all path covers of a DAG

M Cáceres, B Mumey, E Husić, R Rizzi… - IEEE/ACM …, 2021 - ieeexplore.ieee.org
A multi-assembly problem asks to reconstruct multiple genomic sequences from mixed
reads sequenced from all of them. Standard formulations of such problems model a solution …

On the complexity of minimum path cover with subpath constraints for multi-assembly

R Rizzi, AI Tomescu, V Mäkinen - BMC bioinformatics, 2014 - Springer
Background Multi-assembly problems have gathered much attention in the last years, as
Next-Generation Sequencing technologies have started being applied to mixed settings …

Does relaxing the infinite sites assumption give better tumor phylogenies? An ILP-based comparative approach

P Bonizzoni, S Ciccolella… - … /ACM transactions on …, 2018 - ieeexplore.ieee.org
Most of the evolutionary history reconstruction approaches are based on the infinite sites
assumption, which states that mutations appear once in the evolutionary history. The Perfect …

Multitrans: an algorithm for path extraction through mixed integer linear programming for transcriptome assembly

J Zhao, H Feng, D Zhu, Y Lin - IEEE/ACM transactions on …, 2021 - ieeexplore.ieee.org
Recent advances in RNA-seq technology have made identification of expressed genes
affordable, and thus boosting repaid development of transcriptomic studies. Transcriptome …

Explaining a weighted DAG with few paths for solving genome-guided multi-assembly

AI Tomescu, T Gagie, A Popa, R Rizzi… - … ACM transactions on …, 2015 - ieeexplore.ieee.org
RNA-Seq technology offers new high-throughput ways for transcript identification and
quantification based on short reads, and has recently attracted great interest. This is …

Towards the integration, annotation and association of historical microarray experiments with RNA-seq

SS Chavan, MA Bauer, EA Peterson, CJ Heuck… - BMC …, 2013 - Springer
Background Transcriptome analysis by microarrays has produced important advances in
biomedicine. For instance in multiple myeloma (MM), microarray approaches led to the …

Transcriptome assembly and quantification from Ion Torrent RNA-Seq data

S Mangul, A Caciula, S Al Seesi, D Brinza, I Mӑndoiu… - BMC genomics, 2014 - Springer
Background High throughput RNA sequencing (RNA-Seq) can generate whole
transcriptome information at the single transcript level providing a powerful tool with multiple …

Efficient minimum flow decomposition via integer linear programming

FHC Dias, L Williams, B Mumey… - Journal of Computational …, 2022 - liebertpub.com
Minimum flow decomposition (MFD) is an NP-hard problem asking to decompose a network
flow into a minimum set of paths (together with associated weights). Variants of it are …

[图书][B] Computational methods for next generation sequencing data analysis

Y Pan, AY Zomaya - 2016 - books.google.com
Introduces readers to core algorithmic techniques for next-generation sequencing (NGS)
data analysis and discusses a wide range of computational techniques and applications …

Fast, flexible, and exact minimum flow decompositions via ILP

FHC Dias, L Williams, B Mumey, AI Tomescu - … Conference on Research …, 2022 - Springer
Minimum flow decomposition (MFD)—the problem of finding a minimum set of paths that
perfectly decomposes a flow—is a classical problem in Computer Science, and variants of it …