FHODs: Nuclear tethered formins for nuclear mechanotransduction
S Antoku, TU Schwartz, GG Gundersen - Frontiers in Cell and …, 2023 - frontiersin.org
In this review, we discuss FHOD formins with a focus on recent studies that reveal a new role
for them as critical links for nuclear mechanotransduction. The FHOD family in vertebrates …
for them as critical links for nuclear mechanotransduction. The FHOD family in vertebrates …
Novel signaling axis of FHOD1-RNF213-Col1α/Col3α in the pathogenesis of hypertension-induced tunica media thickening
Y Chen, Y Yuan, Y Chen, X Jiang, X Hua… - Journal of Molecular and …, 2023 - Elsevier
Hypertension-induced tunica media thickening (TMT) is the most important fundamental for
the subsequent complications like stroke and cardiovascular diseases. Pathogenically, TMT …
the subsequent complications like stroke and cardiovascular diseases. Pathogenically, TMT …
[HTML][HTML] FHOD-1/profilin-mediated actin assembly protects sarcomeres against contraction-induced deformation in C. elegans
MJ Kimmich, S Sundaramurthy, MA Geary… - bioRxiv, 2024 - ncbi.nlm.nih.gov
Abstract Formin HOmology Domain 2-containing (FHOD) proteins are a subfamily of actin-
organizing formins important for striated muscle development in many animals. We showed …
organizing formins important for striated muscle development in many animals. We showed …
FHOD formin and SRF promote post-embryonic striated muscle growth through separate pathways in C. elegans
CV Yingling, D Pruyne - Experimental cell research, 2021 - Elsevier
Previous work with cultured cells has shown transcription of muscle genes by serum
response factor (SRF) can be stimulated by actin polymerization driven by proteins of the …
response factor (SRF) can be stimulated by actin polymerization driven by proteins of the …
[PDF][PDF] Investigating the roles of the C. elegans formin FHOD-1 in muscle gene expression and actin assembly
C Yingling - 2021 - soar.suny.edu
Muscle growth is important for the proper function of muscle, and dysregulation of muscle
growth can lead to diseases, like hypertrophic and dilated cardiomyopathies. Our work …
growth can lead to diseases, like hypertrophic and dilated cardiomyopathies. Our work …
FHOD formin and SRF promote striated muscle development through separate pathways in C. elegans
CV Yingling, D Pruyne - bioRxiv, 2020 - biorxiv.org
Previous work with cultured cells has shown transcription of muscle genes by serum
response factor (SRF) can be stimulated by actin polymerization driven by proteins of the …
response factor (SRF) can be stimulated by actin polymerization driven by proteins of the …