Biological effects of culture substrates on human pluripotent stem cells

Y Hayashi, MK Furue - Stem cells international, 2016 - Wiley Online Library
In recent years, as human pluripotent stem cells (hPSCs) have been commonly cultured in
feeder‐free conditions, a number of cell culture substrates have been applied or developed …

BMP2 repression and optimized culture conditions promote human bone marrow-derived mesenchymal stem cell isolation

AG Kay, TP Dale, KM Akram, P Mohan… - Regenerative …, 2015 - Taylor & Francis
Aim: Human mesenchymal stem cells (hMSC) are multipotent progenitor cells. We propose
the optimization of hMSC isolation and recovery using the application of a controlled hypoxic …

ESRP1-induced CD44 v3 is important for controlling pluripotency in human pluripotent stem cells

YD Kim, HS Kim, J Lee, JK Choi, E Han, JE Jeong… - Stem Cells, 2018 - academic.oup.com
The importance of alternative splicing (AS) events in pluripotency regulation has been
highlighted by the determination of different roles and contributions of different splice …

Self-renewal of human embryonic stem cells on defined synthetic electrospun nanofibers

D Kumar, TP Dale, Y Yang, NR Forsyth - Biomedical Materials, 2015 - iopscience.iop.org
Human embryonic stem cells (hESCs) are conventionally expanded and maintained in vitro
on biological substrates. Synthetic electrospun polymer nanofibers have the potential to act …

[HTML][HTML] Sufficiency of hypoxia-inducible 2-oxoglutarate dioxygenases to block chemical oxidative stress-induced differentiation of human embryonic stem cells

E Koutsouraki, S Pells, PA De Sousa - Stem Cell Research, 2019 - Elsevier
Hypoxia benefits undifferentiated pluripotent stem cell renewal, and 2-oxoglutarate (2OG)
dioxygenases have been implicated in pluripotent stem cell induction and renewal. We …

Mechanistic analysis of physicochemical cues in promoting human pluripotent stem cell self-renewal and metabolism

N Hai, DW Shin, H Bi, K Ye, S Jin - International Journal of Molecular …, 2018 - mdpi.com
We have previously reported that a porous membrane of polyethylene terephthalate (PET)
enables significant augmentation of human pluripotent stem cell (hPSC) proliferation and …

[PDF][PDF] Understanding Glioblastoma Stem-Like Cells in Quest of a Target to Direct Treatment

JM Gudbergsson - 2020 - vbn.aau.dk
The work presented in this PhD thesis is based on research mainly carried out at Aalborg
University as a part of Laboratory of Cancer Biology. The research conducted is presented in …