Integrin-linked kinase–essential roles in physiology and cancer biology

PC McDonald, AB Fielding… - Journal of cell …, 2008 - journals.biologists.com
Integrin-linked kinase (ILK) is a multifunctional intracellular effector of cell-matrix interactions
and regulates many cellular processes, including growth, proliferation, survival …

The ILK/PINCH/parvin complex: the kinase is dead, long live the pseudokinase!

SA Wickström, A Lange, E Montanez, R Fässler - The EMBO journal, 2010 - embopress.org
Dynamic interactions of cells with their environment regulate multiple aspects of tissue
morphogenesis and function. Integrins are the major class of cell surface receptors that …

Radial glial cell heterogeneity—the source of diverse progeny in the CNS

L Pinto, M Götz - Progress in neurobiology, 2007 - Elsevier
Here, we discuss the identity, heterogeneity and functions of radial glial cells mostly in the
developing central nervous system (CNS). First, we define radial glial cells by …

Origin, lineage and function of cerebellar glia

A Buffo, F Rossi - Progress in neurobiology, 2013 - Elsevier
The glial cells of the cerebellum, and particularly astrocytes and oligodendrocytes, are
characterized by a remarkable phenotypic variety, in which highly peculiar morphological …

Integrin-linked kinase (ILK): the known vs. the unknown and perspectives

A Górska, AJ Mazur - Cellular and Molecular Life Sciences, 2022 - Springer
Integrin-linked kinase (ILK) is a multifunctional molecular actor in cell–matrix interactions,
cell adhesion, and anchorage-dependent cell growth. It combines functions of a signal …

Distinct functions of glial and neuronal dystroglycan in the developing and adult mouse brain

JS Satz, AP Ostendorf, S Hou, A Turner… - Journal of …, 2010 - Soc Neuroscience
Cobblestone (type II) lissencephaly and mental retardation are characteristic features of a
subset of congenital muscular dystrophies that include Walker–Warburg syndrome, muscle …

Basement membrane attachment is dispensable for radial glial cell fate and for proliferation, but affects positioning of neuronal subtypes

N Haubst, E Georges-Labouesse, A De Arcangelis… - 2006 - journals.biologists.com
Radial glial cells have been shown to act as neuronal precursors in the developing cortex
and to maintain their radial processes attached to the basement membrane (BM) during cell …

SPARC from olfactory ensheathing cells stimulates Schwann cells to promote neurite outgrowth and enhances spinal cord repair

E Au, MW Richter, AJ Vincent, W Tetzlaff… - Journal of …, 2007 - Soc Neuroscience
Olfactory ensheathing cells (OECs) transplanted into the lesioned CNS can stimulate
reportedly different degrees of regeneration, remyelination, and functional recovery, but little …

SHH pathway and cerebellar development

C Vaillant, D Monard - The Cerebellum, 2009 - Springer
The morphogenetic factor Sonic hedgehog (SHH) has been discovered as one of the
masterplayers in cerebellar patterning and was subjected to intensive investigation during …

Integrin-linked kinase is required for radial sorting of axons and Schwann cell remyelination in the peripheral nervous system

JA Pereira, Y Benninger, R Baumann… - Journal of Cell …, 2009 - rupress.org
During development, Schwann cells (SCs) interpret different extracellular cues to regulate
their migration, proliferation, and the remarkable morphological changes associated with the …