The synthesis of cyclic peptides
JN Lambert, JP Mitchell, KD Roberts - Journal of the Chemical Society …, 2001 - pubs.rsc.org
Method B makes use of a multicomponent Ugi reaction, wherein a resin-bound amino acid is
reacted with an appropriate aldehyde, isocyanide and second amino acid in a one-pot …
reacted with an appropriate aldehyde, isocyanide and second amino acid in a one-pot …
Enzyme-mimic peptide assembly to achieve amidolytic activity
YM Wong, H Masunaga, JA Chuah, K Sudesh… - …, 2016 - ACS Publications
Amyloid fibers are classified as a new generation of tunable bionanomaterials that exhibit
new functions related to their distinctive characteristics, such as their universality, tunability …
new functions related to their distinctive characteristics, such as their universality, tunability …
Conformational flexibility in designing peptides for immunology: the molecular dynamics approach
A Stavrakoudis - Current Computer-Aided Drug Design, 2010 - ingentaconnect.com
Computational modeling techniques and computer simulations have become a routine in
biological sciences and have gained great attention from researchers. Molecular dynamics …
biological sciences and have gained great attention from researchers. Molecular dynamics …
Evaluation of a two-stage screening procedure in the combinatorial search for serine protease-like activity
A Madder, L Li, H De Muynck, N Farcy… - Journal of …, 2002 - ACS Publications
A series of peptidosteroid derivatives containing two independent peptide chains in which
Ser and His are incorporated were synthesized by solid-phase peptide synthesis. The …
Ser and His are incorporated were synthesized by solid-phase peptide synthesis. The …
TAC-scaffolded tripeptides as artificial hydrolytic receptors: a combinatorial approach toward esterase mimics
HB Albada, RMJ Liskamp - Journal of Combinatorial Chemistry, 2008 - ACS Publications
In this report, we present the first library of tripodal synthetic receptor molecules containing
three different, temporarily N-terminal protected peptide arms capable of performing …
three different, temporarily N-terminal protected peptide arms capable of performing …
[HTML][HTML] Synthesis of functionalised nucleosides for incorporation into nucleic acid-based serine protease mimics
MA Catry, A Madder - Molecules, 2007 - mdpi.com
Molecules | Free Full-Text | Synthesis of Functionalised Nucleosides for Incorporation into
Nucleic Acid-Based Serine Protease Mimics Next Article in Journal Radical-scavenging Activity …
Nucleic Acid-Based Serine Protease Mimics Next Article in Journal Radical-scavenging Activity …
Computational screening of branched cyclic peptide motifs as potential enzyme mimetics
A Stavrakoudis, S Makropoulou… - Journal of peptide …, 2003 - Wiley Online Library
In a previous work we described the design, synthesis and catalytic activity of a branched
cyclic peptide as a serine protease mimic. To maximize its catalytic activity we present now a …
cyclic peptide as a serine protease mimic. To maximize its catalytic activity we present now a …
Solid‐Supported Synthesis of Highly Functionalized Tripodal Peptides with Flexible but Preorganized Geometry: Towards Potential Serine Protease Mimics
A Gea, N Farcy, N Roqué i Rossell, JC Martins… - 2006 - Wiley Online Library
Tripodal scaffold 1 has been used in the synthesis of a representative member of a library of
serine protease mimics, possessing three independent functionalized peptide chains on a …
serine protease mimics, possessing three independent functionalized peptide chains on a …
Molecular Dynamics as a pattern recognition tool: An automated process detects peptides that preserve the 3D arrangement of Trypsin's Active Site
VA Tatsis, A Stavrakoudis, IN Demetropoulos - Biophysical chemistry, 2008 - Elsevier
Recently, the synthesis of a molecule has been reported that belongs to a Lysine based,
branched cyclic peptide class. This work explores the ability of such molecules to preserve …
branched cyclic peptide class. This work explores the ability of such molecules to preserve …
Conformational Studies of the 313-320 and 313-332 Peptide Fragments Derived from the αIIb Subunit of Integrin Receptor with Molecular Dynamics Simulations
A Stavrakoudis - International Journal of Peptide Research and …, 2009 - Springer
The peptide sequence YMESRADRKLAEVGRVYLFL, derived from 313-332 region of the α
IIb, has been identified as a potent inhibitor of platelet aggregation and fibrinogen binding to …
IIb, has been identified as a potent inhibitor of platelet aggregation and fibrinogen binding to …