Roles for RACK1 in cancer cell migration and invasion

D Duff, A Long - Cellular signalling, 2017 - Elsevier
Migration and invasion of cancer cells into surrounding tissue and vasculature is an
important initial step in cancer metastasis. Metastasis is the leading cause of cancer related …

RACK1, a versatile hub in cancer

JJ Li, D Xie - Oncogene, 2015 - nature.com
RACK1 is a highly conserved intracellular adaptor protein with significant homology to Gβ
and was originally identified as the anchoring protein for activated protein kinase C. In the …

RACK1 promotes cancer progression by increasing the M2/M1 macrophage ratio via the NF‐κB pathway in oral squamous cell carcinoma

H Dan, S Liu, J Liu, D Liu, F Yin, Z Wei… - Molecular …, 2020 - Wiley Online Library
Receptor for activated C kinase 1 (RACK1) has been shown to promote oral squamous cell
carcinoma (OSCC) progression, and RACK1 expression levels have been negatively …

Ribosomal proteins as novel players in tumorigenesis

A de Las Heras-Rubio, L Perucho, R Paciucci… - Cancer and Metastasis …, 2014 - Springer
Ribosome biogenesis is the most demanding energetic and metabolic expenditure of the
cell. The nucleolus, a nuclear compartment, coordinates rRNA transcription, maturation, and …

Rack1 mediates tyrosine phosphorylation of Anxa2 by Src and promotes invasion and metastasis in drug-resistant breast cancer cells

Y Fan, W Si, W Ji, Z Wang, Z Gao, R Tian, W Song… - Breast Cancer …, 2019 - Springer
Background Acquirement of resistance is always associated with a highly aggressive
phenotype of tumor cells. Recent studies have revealed that Annexin A2 (Anxa2) is a key …

Ribosomes as a nexus between translation and cancer progression: Focus on ribosomal Receptor for Activated C Kinase 1 (RACK1) in breast cancer

E Buoso, M Masi, A Long, C Chiappini… - British journal of …, 2022 - Wiley Online Library
Ribosomes coordinate spatiotemporal control of gene expression, contributing to the
acquisition and maintenance of cancer phenotype. The link between ribosomes and cancer …

Hypoxia-inducible factor–1 and associated upstream and downstream proteins in the pathophysiology and management of glioblastoma

M Womeldorff, D Gillespie, RL Jensen - Neurosurgical focus, 2014 - thejns.org
Glioblastoma multiforme (GBM) is a highly aggressive brain tumor with an exceptionally
poor patient outcome despite aggressive therapy including surgery, radiation, and …

PA28γ acts as a dual regulator of IL-6 and CCL2 and contributes to tumor angiogenesis in oral squamous cell carcinoma

S Liu, D Liu, X Zeng, J Wang, J Liu, J Cheng, K Lei… - Cancer letters, 2018 - Elsevier
PA28γ promotes tumor development and progression and is suggested to play a role in
tumor angiogenesis, but the molecular mechanisms have not been investigated. Here, we …

RACK1 promotes the proliferation, migration and invasion capacity of mouse hepatocellular carcinoma cell line in vitro probably by PI3K/Rac1 signaling pathway

J Wu, J Meng, Y Du, Y Huang, Y Jin, J Zhang… - Biomedicine & …, 2013 - Elsevier
Hca-P and Hca-F is a pair of synogenetic mouse hepatocarcinoma ascites cell lines,
possessing different capacity of lymphatic metastasis. Receptor of activated C-kinase 1 …

[HTML][HTML] The receptor for activated protein kinase C promotes cell growth, invasion and migration in cervical cancer

S Liao, S Xiao, H Chen, M Zhang… - International …, 2017 - spandidos-publications.com
Cervical cancer is one of the most common malignant tumors in women all over the world.
However, the exact etiology of cervical cancer remains unclear. The receptor for activated …