Molecular mechanisms and physiological importance of circadian rhythms
A Patke, MW Young, S Axelrod - Nature reviews Molecular cell biology, 2020 - nature.com
To accommodate daily recurring environmental changes, animals show cyclic variations in
behaviour and physiology, which include prominent behavioural states such as sleep–wake …
behaviour and physiology, which include prominent behavioural states such as sleep–wake …
[HTML][HTML] Social jetlag and related risks for human health: a timely review
R Caliandro, AA Streng, LWM van Kerkhof… - Nutrients, 2021 - mdpi.com
The term social jetlag is used to describe the discrepancy between biological time,
determined by our internal body clock, and social times, mainly dictated by social obligations …
determined by our internal body clock, and social times, mainly dictated by social obligations …
Transcriptional architecture of the mammalian circadian clock
JS Takahashi - Nature Reviews Genetics, 2017 - nature.com
Circadian clocks are endogenous oscillators that control 24-hour physiological and
behavioural processes in organisms. These cell-autonomous clocks are composed of a …
behavioural processes in organisms. These cell-autonomous clocks are composed of a …
[HTML][HTML] Genomics of circadian rhythms in health and disease
F Rijo-Ferreira, JS Takahashi - Genome medicine, 2019 - Springer
Circadian clocks are endogenous oscillators that control 24-h physiological and behavioral
processes. The central circadian clock exerts control over myriad aspects of mammalian …
processes. The central circadian clock exerts control over myriad aspects of mammalian …
[HTML][HTML] Interplay between metabolism and epigenetics: a nuclear adaptation to environmental changes
JP Etchegaray, R Mostoslavsky - Molecular cell, 2016 - cell.com
The physiological identity of every cell is maintained by highly specific transcriptional
networks that establish a coherent molecular program that is in tune with nutritional …
networks that establish a coherent molecular program that is in tune with nutritional …
Molecular components of the Mammalian circadian clock
ED Buhr, JS Takahashi - Circadian clocks, 2013 - Springer
Mammals synchronize their circadian activity primarily to the cycles of light and darkness in
the environment. This is achieved by ocular photoreception relaying signals to the …
the environment. This is achieved by ocular photoreception relaying signals to the …
[HTML][HTML] A simple and effective F0 knockout method for rapid screening of behaviour and other complex phenotypes
Hundreds of human genes are associated with neurological diseases, but translation into
tractable biological mechanisms is lagging. Larval zebrafish are an attractive model to …
tractable biological mechanisms is lagging. Larval zebrafish are an attractive model to …
Metabolism and the circadian clock converge
K Eckel-Mahan, P Sassone-Corsi - Physiological reviews, 2013 - journals.physiology.org
Circadian rhythms occur in almost all species and control vital aspects of our physiology,
from sleeping and waking to neurotransmitter secretion and cellular metabolism …
from sleeping and waking to neurotransmitter secretion and cellular metabolism …
[HTML][HTML] The mammalian circadian system: a hierarchical multi-oscillator structure for generating circadian rhythm
S Honma - The Journal of Physiological Sciences, 2018 - Springer
The circadian nature of physiology and behavior is regulated by a circadian clock that
generates intrinsic rhythms with a periodicity of approximately 24 h. The mammalian …
generates intrinsic rhythms with a periodicity of approximately 24 h. The mammalian …
Physiology of circadian entrainment
DA Golombek, RE Rosenstein - Physiological reviews, 2010 - journals.physiology.org
Mammalian circadian rhythms are controlled by endogenous biological oscillators, including
a master clock located in the hypothalamic suprachiasmatic nuclei (SCN). Since the period …
a master clock located in the hypothalamic suprachiasmatic nuclei (SCN). Since the period …