[HTML][HTML] Vascular ageing: mechanisms, risk factors, and treatment strategies
J Ya, U Bayraktutan - International Journal of Molecular Sciences, 2023 - mdpi.com
Ageing constitutes the biggest risk factor for poor health and adversely affects the integrity
and function of all the cells, tissues, and organs in the human body. Vascular ageing …
and function of all the cells, tissues, and organs in the human body. Vascular ageing …
BrainAGE, brain health, and mental disorders: A systematic review
The imaging-based method of brainAGE aims to characterize an individual's vulnerability to
age-related brain changes. The present study systematically reviewed brainAGE findings in …
age-related brain changes. The present study systematically reviewed brainAGE findings in …
[HTML][HTML] Environmental and genetic predictors of human cardiovascular ageing
Cardiovascular ageing is a process that begins early in life and leads to a progressive
change in structure and decline in function due to accumulated damage across diverse cell …
change in structure and decline in function due to accumulated damage across diverse cell …
[HTML][HTML] Neuroimaging-based brain age estimation: A promising personalized biomarker in neuropsychiatry
D Sone, I Beheshti - Journal of Personalized Medicine, 2022 - mdpi.com
It is now possible to estimate an individual's brain age via brain scans and machine-learning
models. This validated technique has opened up new avenues for addressing clinical …
models. This validated technique has opened up new avenues for addressing clinical …
[HTML][HTML] Comparison of machine learning models for brain age prediction using six imaging modalities on middle-aged and older adults
Machine learning (ML) has transformed neuroimaging research by enabling accurate
predictions and feature extraction from large datasets. In this study, we investigate the …
predictions and feature extraction from large datasets. In this study, we investigate the …
[HTML][HTML] Novel pharmacological strategies to treat cognitive dysfunction in chronic obstructive pulmonary disease
Chronic obstructive pulmonary disease (COPD) is a major incurable global health burden
and currently the 3rd largest cause of death in the world, with approximately 3.23 million …
and currently the 3rd largest cause of death in the world, with approximately 3.23 million …
Evaluating the causal effect of tobacco smoking on white matter brain aging: a two‐sample Mendelian randomization analysis in UK Biobank
Abstract Background and Aims Tobacco smoking is a risk factor for impaired brain function,
but its causal effect on white matter brain aging remains unclear. This study aimed to …
but its causal effect on white matter brain aging remains unclear. This study aimed to …
Associations between polygenic risk scores and accelerated brain ageing in smokers
BackgroundSmoking contributes to a variety of neurodegenerative diseases and
neurobiological abnormalities, suggesting that smoking is associated with accelerated brain …
neurobiological abnormalities, suggesting that smoking is associated with accelerated brain …
[HTML][HTML] Association between cumulative smoking exposure and cognitive decline in non-demented older adults: NEDICES study
J Benito-León, R Ghosh, J Lapeña-Motilva… - Scientific reports, 2023 - nature.com
Whether cumulative smoking exposure is associated with cognitive decline among older
adults remains unresolved. To address this question, we used data from the Neurological …
adults remains unresolved. To address this question, we used data from the Neurological …
Associations between differential aging and lifestyle, environment, current, and future health conditions: Findings from Canadian Longitudinal Study on Aging
Introduction: An aging population will bring a pressing challenge for the healthcare system.
Insights into promoting healthy longevity can be gained by quantifying the biological aging …
Insights into promoting healthy longevity can be gained by quantifying the biological aging …