Catalytic Enantioselective Intramolecular Oxa-Michael Reaction to α, β-Unsaturated Esters and Amides

G Su, M Formica, K Yamazaki, TA Hamlin… - Journal of the …, 2023 - ACS Publications
A bifunctional iminophosphorane (BIMP)-catalyzed, enantioselective intramolecular oxa-
Michael reaction of alcohols to tethered, low electrophilicity Michael acceptors is described …

Copper‐Catalyzed Asymmetric Synthesis of Silicon‐Stereogenic Benzoxasiloles

WE Gan, YS Wu, B Wu, CY Fang, J Cao… - Angewandte …, 2024 - Wiley Online Library
A Cu‐catalyzed asymmetric synthesis of silicon‐stereogenic benzoxasiloles has been
realized via intramolecular Si− O coupling of [2‐(hydroxymethyl) phenyl] silanes. Cu …

Enantioselective palladium-catalyzed diarylation of unactivated alkenes

B Ju, S Chen, W Kong - Chemical Communications, 2019 - pubs.rsc.org
Enantioselective Pd-catalyzed diarylation of unactivated alkenes between arenediazonium
salts and arylboronic acids has been developed. This method provides an efficient route to …

Synthesis of 1, 3-diselenyl-dihydroisobenzofurans via electrochemical radical selenylation with substituted o-divinylbenzenes and diselenides

Y Wang, N Xu, W Li, J Li, Y Huo, W Zhu… - Organic & Biomolecular …, 2022 - pubs.rsc.org
An efficient electrochemical method for the direct synthesis of complicated 1, 3-diselenyl-
dihydroisobenzofurans was developed under external oxidant free conditions at room …

Designing of 2, 3-dihydrobenzofuran derivatives as inhibitors of PDE1B using pharmacophore screening, ensemble docking and molecular dynamics approach

M Al-Nema, A Gaurav, VS Lee - Computers in Biology and Medicine, 2023 - Elsevier
In recent years, the PDE1B enzyme has become a desirable drug target for the treatment of
psychological and neurological disorders, particularly schizophrenia disorder, due to the …

Synergistic Palladium/Chiral Phosphoric Acid-Catalyzed Kinetic Resolution via Stereoselective Intramolecular Substitution of Unactivated Allylic Alcohols

CT Chou, CW Lu, BS Wu, CC Tsai - The Journal of Organic …, 2023 - ACS Publications
This paper reports the kinetic resolution of racemic secondary alcohols (O-nucleophiles) via
stereoselective intramolecular allylic substitution. The reaction was enabled by synergistic …

Integrating bio-oil and carbohydrate valorization on the fractionation of sugarcane bagasse via Organosolv process using Mo2C-based catalysts

GT Wurzler, VT da Silva, D de Almeida Azevedo… - Fuel Processing …, 2022 - Elsevier
This work studied the fractionation of sugarcane bagasse via Organosolv treatment using
isopropanol/water in the presence of Raney-Ni and molybdenum carbide catalysts (Bulk Mo …

Synthesis of 1, 1, 4, 5-Tetrasubstituted Phthalans via Pd-Catalyzed Three-Component Reactions of Haloarenes, Alkynes, and Protic Nucleophiles

W Huang, H Wang, B Liu, R Shen, S Zhu - Organic Letters, 2022 - ACS Publications
A novel approach for the synthesis of 1, 1, 4, 5-tetrasubstituted phthalans is developed via a
tandem palladium-catalyzed Sonogashira coupling/propargyl–allenyl isomerization …

Oxidative generation of isobenzofurans from phthalans: application to the formal synthesis of (±)-morphine

M Kage, H Yamakoshi, M Tabata, E Ohashi… - Chemical …, 2024 - pubs.rsc.org
Treatment of phthalan derivatives with p-chloranil in dodecane in the presence of molecular
sieves at 160–200° C allowed the generation of unstabilized isobenzofurans, which …

Synergistic asymmetric diarylation of tethered alkenes via C–H functionalization of simple (hetero)arenes

J Yao, C Zhao, L Shao, X Huo, X Wang - Science China Chemistry, 2024 - Springer
By virtue of the atom-and step-economy, utilization of simple arenes as a supplant of pre-
prepared aryl metal species or aryl halides for the synthesis of arylated chiral molecules has …