The first studies suggesting that abnormal expression of galectins is associated with cancer
were published more than 30 years ago. Today, the role of galectins in cancer is relatively …

In humans, a total of 12 galectins have been identified. Their intracellular and extracellular
biological functions are explored and discussed in this review. These galectins play …

Galectins are a family of soluble β-galactoside-binding proteins with diverse glycan-
dependent and glycan-independent functions outside and inside the cell. Human cells …

Background The structure of human galectin-16 (Gal-16) has yet to be solved, and its
function has remained elusive. Methods X-ray crystallography was used to determine the …

Autophagy is a vital physiological process that maintains intracellular homeostasis by
removing damaged organelles and senescent or misfolded molecules. However, excessive …

The expression of prototype galectin‐14 (Gal‐14) in human placenta is higher than any
other galectin, suggesting that it may play a role in fetal development and regulation of …

In the galectin family, a group of lectins is united by their evolutionarily conserved
carbohydrate recognition domains. These polypeptides play a role in various cellular …

With 1.5 million new infections and 690,000 AIDS-related deaths globally each year, HIV-1
remains a pathogen of significant public health concern. Although a wide array of effective …

Galectins are a phylogenetically conserved family of soluble β-galactoside binding proteins.
There are 16 different of galectins, each with a specific function determined by its distinct …

Abstract Charcot-Leyden crystals (CLCs) are the hallmark of many eosinophilic-based
diseases, such as asthma. Here, we report that reduced glutathione (GSH) disrupts CLCs …