The subversion of toll-like receptor signaling by bacterial and viral proteases during the development of infectious diseases

I Ciaston, E Dobosz, J Potempa, J Koziel - Molecular aspects of medicine, 2022 - Elsevier
Toll-like receptors (TLRs) are pattern recognition receptors (PRRs) that respond to pathogen-
associated molecular patterns (PAMPs). The recognition of specific microbial ligands by …

Immunosenescence and inflammaging: Conspiracies against alveolar bone turnover

F Zhou, Z Wang, G Zhang, Y Wu, Y Xiong - Oral Diseases, 2024 - Wiley Online Library
Objective Inflammaging and immunosenescence are characteristics of senescent immune
system alterations. This review provides insights into inflammaging and immunosenescence …

Inflammatory macrophages exploited by oral streptococcus increase IL-1B release via NLRP6 inflammasome

S Metcalfe, M Panasiewicz… - Journal of Leukocyte …, 2023 - academic.oup.com
Chronic inflammatory periodontal disease develops in part from the infiltration of a large
number of classically activated inflammatory macrophages that release inflammatory …

Proteolytic activity-independent activation of the immune response by gingipains from Porphyromonas gingivalis

I Ciaston, J Budziaszek, D Satala, B Potempa, A Fuchs… - Mbio, 2022 - Am Soc Microbiol
Porphyromonas gingivalis, a keystone pathogen in periodontitis (PD), produces cysteine
proteases named gingipains (RgpA, RgpB, and Kgp), which strongly affect the host immune …

Nociceptors regulate osteoimmune transcriptomic response to infection

KV Lillis, O Austah, R Grinceviciute, GP Garlet… - Scientific reports, 2023 - nature.com
Osteoimmune diseases, such as apical periodontitis, are prevalent, often painful,
inflammatory conditions resulting in bone loss and reduced quality of life. There is growing …

MCPIP1 alleviates inflammatory response through inducing autophagy in Aspergillus fumigatus keratitis

F Han, L Shen, H Ma, L Wang, H Guo, X Wu - International …, 2022 - Elsevier
Fungal keratitis (FK) is a serious corneal infection caused by pathogenic fungi. Monocyte
chemoattractant protein-induced protein 1 (MCPIP1) plays an important role in restricting the …

Localization and expression profiles of gingival monocyte chemoattractant protein-1-induced protein-1 (MCPIP-1) and mucosa-associated lymphoid tissue lymphoma …

L Yu, Y Firatli, S Elmanfi, M Gürsoy… - Clinical Oral …, 2023 - Springer
Objectives The purposes of this study were to localize monocyte chemoattractant protein-1-
induced protein-1 (MCPIP-1) and its suppressor mucosa-associated lymphoid tissue …

Regulation of gingival keratinocyte monocyte chemoattractant protein‐1‐induced protein (MCPIP)‐1 and mucosa‐associated lymphoid tissue lymphoma translocation …

Y Firatli, E Firatli, V Loimaranta… - Journal of …, 2023 - Wiley Online Library
Background The aim of this study was to evaluate oral bacteria‐and interleukin (IL)‐1β‐
induced protein and mRNA expression profiles of monocyte chemoattractant protein‐1 …

Periodontal and microbiological data in patients with mucous membrane pemphigoid in a French population in 2021–2022: A pilot cross‐sectional study

AL Ejeil, F Gaultier, B Catherine… - Health Science …, 2024 - Wiley Online Library
Abstract Background and Aims In the case of mucous membrane pemphigoid with gingival
expression (gMMP), the complete healing of the gingiva is generally not achieved despite …

[PDF][PDF] Identification and Characterization of Surface Adhesive Proteins of Prevotella Intermedia that Bind to Saliva and Extracellular Matrix Proteins

N Akentieva - 2024 - researchgate.net
Adhesin proteins Prevotella intermedia mediate the attachment of bacteria to host cells and
thereby induce the development of periodontal disease. These adhesin proteins are …