What if not all metabolites from the uremic toxin generating pathways are toxic? A hypothesis

R Vanholder, SK Nigam, S Burtey, G Glorieux - Toxins, 2022 - mdpi.com
The topic of uremic toxicity has received broad attention from the nephrological community
over the past few decades. An aspect that is much less often considered is the possibility …

Lessons learned during the war in Ukraine: a report from the Renal Disaster Relief Task Force of the ERA

S Tuğlular, V Luyckx, R Vanholder… - Nephrology Dialysis …, 2023 - academic.oup.com
People living with kidney disease are among the most vulnerable at times of natural or man-
made disasters. In addition to their unpredictable course, armed conflicts impose a major …

Treating multi-drug-resistant bacterial infections by functionalized nano-bismuth sulfide through the synergy of immunotherapy and bacteria-sensitive phototherapy

Y Li, X Liu, Z Cui, Y Zheng, H Jiang, Y Zhang, Y Liang… - ACS …, 2022 - ACS Publications
Owing to its flexibility and high treatment efficiency, phototherapy is rapidly emerging for
treating bacteria-induced diseases, but how to improve the sensitivity of bacteria to reactive …

Rationale for a new classification of solutes of interest in chronic kidney disease and hemodialysis

T Reis, C Hutchison, F de Assis Rocha Neves… - Blood …, 2023 - karger.com
A hallmark of chronic kidney disease is the retention of solutes that normally are eliminated
by the kidneys. The current classification defines uremic toxins based on molecular weight …

The European Kidney Health Alliance (EKHA) and the Decade of the KidneyTM

R Vanholder, PT Conway, D Gallego… - Nephrology Dialysis …, 2023 - academic.oup.com
Abstract The European Kidney Health Alliance (EKHA) is an advocacy organization that
defends the case of the kidney patients and the nephrological community at the level of the …

[PDF][PDF] Enhancing Immune Protection in Hemodialysis Patients: Role of the Polymethyl Methacrylate Membrane

R Franzin, A Stasi, G Caggiano, E Squiccimarro… - Blood …, 2023 - karger.com
End-stage renal disease (ESRD) is characterized by deep disorders in both innate and
adaptive immune systems that imply unbalance deactivation and immunosuppression. The …

Toward an individualized determination of dialysis adequacy: a narrative review with special emphasis on incremental hemodialysis

M Torreggiani, A Fois, L Njandjo… - Expert Review of …, 2021 - Taylor & Francis
Introduction The search for the 'perfect'renal replacement therapy has been paralleled by the
search for the perfect biomarkers for assessing dialysis adequacy. Three main families of …

Longitudinal plasma metabolome patterns and relation to kidney function and proteinuria in pediatric chronic kidney disease

AM Lee, Y Xu, J Hu, R Xiao, SR Hooper… - Clinical Journal of the …, 2024 - journals.lww.com
Methods The Chronic Kidney Disease in Children (CKiD) study is a multi-institutional,
prospective cohort that enrolled children aged six-months to 16-years with estimated …

Early treatment with 2-deoxy-d-glucose reduces proliferative proteins in the kidney and slows cyst growth in a hypomorphic Pkd1 mouse model of autosomal dominant …

D Atwood, Z He, M Miyazaki, F Hailu, J Klawitter… - Cellular …, 2024 - Elsevier
In autosomal dominant polycystic kidney disease (ADPKD) there is cyst growth in the
kidneys that leads to chronic kidney disease often requiring dialysis or kidney …

[HTML][HTML] Indoxyl Sulfate Contributes to Impaired Height Velocity in (Pre) School Children

E Snauwaert, S De Buyser, W Van Biesen… - Kidney international …, 2024 - Elsevier
Introduction Growth failure is considered the most important clinical outcome parameter in
childhood chronic kidney disease (CKD). Central to the pathophysiology of growth failure is …