Role of serum level and genetic variation of IL-28B in interferon responsiveness and advanced liver disease in chronic hepatitis C patients
Abstract Interleukin-28B (IL-28B) is suspected to be associated with response to treatment
and one of the basic immunological backgrounds in liver transplant candidate (LTC). We …
and one of the basic immunological backgrounds in liver transplant candidate (LTC). We …
Association of mutations in the NS5A-PKRBD region and IFNL4 genotypes with hepatitis c interferon responsiveness and its functional and structural analysis
Background: The cellular antiviral responses induced by interferons require some cellular
protein kinase for its activation. Evidence indicated that a number of Hepatitis C Virus (HCV) …
protein kinase for its activation. Evidence indicated that a number of Hepatitis C Virus (HCV) …
[HTML][HTML] Interferon-λ polymorphisms and response to pegylated interferon in Iranian hepatitis C patients
A Haj-Sheykholeslami, M Keshvari… - World Journal of …, 2015 - ncbi.nlm.nih.gov
AIM: To evaluate the efficacy of pegylated interferon in Iranian chronic hepatitis C patients in
relation to interferon-λ (IFNL) polymorphisms. METHODS: This study enrolled patients with …
relation to interferon-λ (IFNL) polymorphisms. METHODS: This study enrolled patients with …
Association of IL28 B and IL10 polymorphism with HCV infection and direct antiviral treatment
K Junaid, H Rasool, A ul Mustafa… - Annals of Clinical & …, 2021 - Assoc Clin Scientists
Objective Single nucleotide polymorphisms (SNPs) in IL28B and IL10 regions are important
in predicting the antiviral response in hepatitis C virus (HCV) patients. In this study, the …
in predicting the antiviral response in hepatitis C virus (HCV) patients. In this study, the …
[HTML][HTML] The impact of IL28B genotype and liver fibrosis on the hepatic expression of IP10, IFI27, ISG15, and MX1 and their association with treatment outcomes in …
K Domagalski, M Pawłowska, D Kozielewicz… - PLoS …, 2015 - journals.plos.org
The strong impact of interleukin 28B (IL28B) polymorphisms on sustained virological
response (SVR) after peginterferon and ribavirin treatment in patients with chronic hepatitis …
response (SVR) after peginterferon and ribavirin treatment in patients with chronic hepatitis …
IL28B rs12980275 and HLA rs4273729 genotypes as a powerful predictor factor for rapid, early, and sustained virologic response in patients with chronic hepatitis C
Single-nucleotide polymorphisms (SNPs) in the Interleukin-28B (IL28B) gene and
rs4273729 in the human leukocyte antigen (HLA) gene in chronic hepatitis C (CHC) virus …
rs4273729 in the human leukocyte antigen (HLA) gene in chronic hepatitis C (CHC) virus …
Are statins a viable option for the treatment of infections with the hepatitis C virus?
Abstract Statins are 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors
that are widely used for the treatment of hypercholesterolemia. Besides their cholesterol …
that are widely used for the treatment of hypercholesterolemia. Besides their cholesterol …
Polymorphisms at IL28B gene as predictors of viral relapse in genotype 4 Egyptian hepatitis C patients
Chronic HCV is one of the commonest causes of chronic liver disease worldwide with about
15% of population infected in Egypt. Certain single nucleotide polymorphisms (SNPs) lying …
15% of population infected in Egypt. Certain single nucleotide polymorphisms (SNPs) lying …
IL28B polymorphism (rs12979860) associated with clearance of HCV infection in Poland: Systematic review of its prevalence in chronic hepatitis C patients and …
MP Kaczor, M Seczyńska, W Szczeklik… - Pharmacological Reports, 2015 - Elsevier
Background A common single nucleotide polymorphism (rs12979860) of the interleukin-28B
(IL28B) gene is strongly associated with spontaneous and treatment-related eradication of …
(IL28B) gene is strongly associated with spontaneous and treatment-related eradication of …
[PDF][PDF] Study of Interleukin 28B rs12979860 and rs8099917 Polymorphisms and T-helper 1 Response in Hepatitis C Virus Patients
EA Rashwan, AA Ghazy, AG El-Sheredy… - EGYPTIAN JOURNAL …, 2015 - researchgate.net
HCV infection is a serious public health problem and a leading cause of chronic liver
disease. It affects nearly 3% of the world's population with an associated high mortality …
disease. It affects nearly 3% of the world's population with an associated high mortality …