Inflammageing: chronic inflammation in ageing, cardiovascular disease, and frailty

L Ferrucci, E Fabbri - Nature Reviews Cardiology, 2018 - nature.com
Most older individuals develop inflammageing, a condition characterized by elevated levels
of blood inflammatory markers that carries high susceptibility to chronic morbidity, disability …

Lipid management in patients with chronic kidney disease

CJ Ferro, PB Mark, M Kanbay, P Sarafidis… - Nature Reviews …, 2018 - nature.com
An increased risk of cardiovascular disease, independent of conventional risk factors, is
present even at minor levels of renal impairment and is highest in patients with end-stage …

The impact of SGLT2 inhibitors on inflammation: A systematic review and meta-analysis of studies in rodents

P Theofilis, M Sagris, E Oikonomou… - International …, 2022 - Elsevier
Background Inhibition of sodium-glucose cotransporter-2 (SGLT2) has received remarkable
attention due to the beneficial effects observed in diabetes mellitus, heart failure, and kidney …

Slipping through the pores: hypoalbuminemia and albumin loss during hemodialysis

K Kalantar-Zadeh, LH Ficociello… - … journal of nephrology …, 2021 - Taylor & Francis
Hypoalbuminemia results when compensatory mechanisms are unable to keep pace with
derangements in catabolism/loss and/or decreased synthesis of albumin. Across many …

Exercise in patients with hypertension and chronic kidney disease: a randomized controlled trial

FC Barcellos, FB Del Vecchio, A Reges… - Journal of human …, 2018 - nature.com
Hypertension and chronic kidney disease (CKD) are global public health problems, both
associated with higher risk of cardiovascular (CV) and renal events. This trial randomized …

[HTML][HTML] Impact of C-reactive protein on osteo-/chondrogenic transdifferentiation and calcification of vascular smooth muscle cells

LA Henze, TTD Luong, B Boehme, J Masyout… - Aging (Albany …, 2019 - ncbi.nlm.nih.gov
Medial vascular calcification occurs during the aging process and is strongly accelerated by
chronic kidney disease (CKD). Elevated C-reactive protein (CRP) levels are associated with …

[HTML][HTML] Lowering LDL cholesterol reduces cardiovascular risk independently of presence of inflammation

BC Storey, N Staplin, R Haynes, C Reith, J Emberson… - Kidney international, 2018 - Elsevier
Markers of inflammation, including plasma C-reactive protein (CRP), are associated with an
increased risk of cardiovascular disease, and it has been suggested that this association is …

Advances in aptamer-based sensing assays for C-reactive protein

MQ Tang, J Xie, LM Rao, YJ Kan, P Luo… - Analytical and …, 2022 - Springer
Abstract C-reactive protein (CRP), a non-specific acute-phase indicator of inflammation, has
been widely recognized for its value in clinical diagnostic applications. With the …

[HTML][HTML] Urinary uromodulin independently predicts end-stage renal disease and rapid kidney function decline in a cohort of chronic kidney disease patients

D Steubl, M Block, V Herbst, WA Nockher… - Medicine, 2019 - journals.lww.com
Data on risk factors predicting rapid progression to end-stage renal disease (ESRD) or short-
term kidney function decline (ie, within 1 year) in chronic kidney disease (CKD) are rare but …

[HTML][HTML] Anemia modifies the prognostic value of glycated hemoglobin in patients with diabetic chronic kidney disease

IC Kuo, HYH Lin, SW Niu, JJ Lee, YW Chiu, CC Hung… - PloS one, 2018 - journals.plos.org
A common complication of chronic kidney disease (CKD), anemia can influence glycated
hemoglobin (HbA1c) levels. In diabetic patients, anemia occurs earlier and with higher …