Background: Migraine is a chronic neurological disorder characterized by attacks of
moderate or severe headache and various neurological symptoms. Migraine is typically …

Acupuncture is commonly used as a treatment for migraines. Animal studies have suggested
that acupuncture can decrease neuropeptides, immune cells, and proinflammatory and …

Objective To investigate the whole-brain resting-state functional connectivity in patients with
chronic migraine (CM) using a data-driven method. Methods We prospectively recruited …

Background The majority of individuals with post-traumatic headache have symptoms that
are indistinguishable from migraine. The overlap in symptoms amongst these individuals …

Background The precuneus/posterior cingulate cortex, which has been associated with pain
sensitivity, plays a pivotal role in the default mode network. However, information regarding …

Introduction We aimed to evaluate the efficacy of electroacupuncture in relieving acute pain
after total knee arthroplasty (TKA) and related mechanism. Methods In this randomized …

The perception of pain is strongly influenced by cognitive processes, such as expectations
toward the efficacy of pain medication. It is reasonable to assume that such processes …

Background and purpose Migraine is a complex and disabling neurological disorder, the
exact neurological mechanisms of which remain unclear. The thalamus is considered to be …

Purpose This study aimed to explore the changes in gamma-aminobutyric acid (GABA) and
glutamate (Glu) levels, and their correlations with clinical indicators in patients with …

The rise of functional magnetic resonance imaging (fMRI) has led to a deeper understanding
of cortical processing of pain. Central to these advances has been the identification and …