Biocatalysis has undergone revolutionary progress in the past century. Benefited by the
integration of multidisciplinary technologies, natural enzymatic reactions are constantly …

All organisms produce specialized organic molecules, ranging from small volatile chemicals
to large gene-encoded peptides, that have evolved to provide them with diverse cellular and …

The Chilean soapbark tree (Quillaja saponaria) produces soap-like molecules called QS
saponins that are important vaccine adjuvants. These highly valuable compounds are …

INTRODUCTION Specialized metabolism is a feature of plant evolution and adaption. Plant-
specialized metabolites have ecological functions, mediating interactions between plants …

Covering: up to 2022 Pentacyclic triterpenoids are important natural bioactive substances
that are widely present in plants and fungi. They have significant medicinal efficacy, play an …

QS-21 is a potent vaccine adjuvant currently sourced by extraction from the Chilean
soapbark tree. It is a key component of human vaccines for shingles, malaria, coronavirus …

The screening and testing of extracts against a variety of pharmacological targets in order to
benefit from the immense natural chemical diversity is a concern in many laboratories …

Triterpenes with complex scaffold modifications are widespread in the plant kingdom.
Limonoids are an exemplary family that are responsible for the bitter taste in citrus (eg …

Plant specialized terpenoids are natural products that have no obvious role in growth and
development, but play many important functional roles to improve the plant's overall fitness …

Triterpenoids are among the most assorted class of specialized metabolites found in all the
taxa of living organisms. Triterpenoids are the leading active ingredients sourced from plant …