Background Craving is viewed as a major determinant of relapse in persons with substance
addiction, but this association remains poorly understood due to its time-limited nature and …

Relapse is a highly prevalent phenomenon in addiction. This paper examines the new
research on identifying biological factors that contribute to addiction relapse risk …

The COVID-19 pandemic disproportionately disrupts the daily lives of marginalized
populations. Persons with substance use disorders are a particularly vulnerable population …

Introduction: The current study aims to evaluate if and to what extent mindfulness-based
interventions (MBIs) could promote an incremental effectiveness compared to interventions …

Background Opioid-induced hyperalgesia (OIH) is well documented in preclinical studies,
but findings of clinical studies are less consistent. The objective was to undertake a …

Highlights•Conceptualization of craving and its inclusion as a symptom in DSM-V.•Incentive
salience and wanting: a dimensional view of craving, ranging from normal healthy desire to …

Rationale and background High relapse rates during abstinence are a pervasive problem in
drug addiction treatment. Relapse is often associated with stress exposure, which can …

Background Studies of sex differences have shown that men and women with drug-use
disorders differ in course and outcome and in cue-induced activation of putative brain …

ABSTRACT Background and Aims Cocaine use disorder (CUD) is a significant public health
concern for which no efficacious pharmacological interventions are available. Cannabidiol …

Background Despite recognition of the negative impact of psychiatric comorbidity on
addictive disorders, the mechanisms underlying this association remain poorly understood …