Ru (II) compounds: next-generation anticancer metallotherapeutics?
Metal based therapeutics are a precious class of drugs in oncology research that include
examples of theranostic drugs, which are active in both diagnostic, specifically imaging, and …
examples of theranostic drugs, which are active in both diagnostic, specifically imaging, and …
[HTML][HTML] Anticancer ruthenium (III) complexes and Ru (III)-containing nanoformulations: An update on the mechanism of action and biological activity
The great advances in the studies on metal complexes for the treatment of different cancer
forms, starting from the pioneering works on platinum derivatives, have fostered an …
forms, starting from the pioneering works on platinum derivatives, have fostered an …
Synthesis, characterization of ruthenium (II), nickel (II), palladium (II), and platinum (II) triphenylphosphine-based complexes bearing an ONS-donor chelating agent …
SA Elsayed, HE Badr, A di Biase… - Journal of Inorganic …, 2021 - Elsevier
Four new transition metal complexes,[M (PPh 3)(L)]. CH 3 OH (M= Ni (II)(1), Pd (II)(2))[Pt
(PPh 3) 2 (HL)] Cl (3) and [Ru (CO)(PPh 3) 2 (L)](4)(H 2 L= 2, 4-dihydroxybenzaldehyde-S …
(PPh 3) 2 (HL)] Cl (3) and [Ru (CO)(PPh 3) 2 (L)](4)(H 2 L= 2, 4-dihydroxybenzaldehyde-S …
Triarylphosphine-coordinated bipyridyl Ru (II) complexes induce mitochondrial dysfunction
RJ Mitchell, AS Gowda, AG Olivelli… - Inorganic …, 2023 - ACS Publications
While cancer cells rely heavily upon glycolysis to meet their energetic needs, reducing the
importance of mitochondrial oxidative respiration processes, more recent studies have …
importance of mitochondrial oxidative respiration processes, more recent studies have …
Anticancer effects of phytol against Sarcoma (S-180) and Human Leukemic (HL-60) cancer cells
MVOB de Alencar, MT Islam, AMOF da Mata… - … Science and Pollution …, 2023 - Springer
Abstract Phytol (Pyt), a diterpenoid, possesses many important bioactivities. This study
evaluates the anticancer effects of Pyt on sarcoma 180 (S-180) and human leukemia (HL …
evaluates the anticancer effects of Pyt on sarcoma 180 (S-180) and human leukemia (HL …
[HTML][HTML] Synthesis of Pd/Ru Bimetallic Nanoparticles by Escherichia coli and Potential as a Catalyst for Upgrading 5-Hydroxymethyl Furfural Into Liquid Fuel …
J Gomez-Bolivar, IP Mikheenko, RL Orozco… - Frontiers in …, 2019 - frontiersin.org
Escherichia coli cells support the nucleation and growth of ruthenium and ruthenium-
palladium nanoparticles (Bio-Ru and Bio-Pd/Ru NPs). We report a method for the synthesis …
palladium nanoparticles (Bio-Ru and Bio-Pd/Ru NPs). We report a method for the synthesis …
Light-triggered dissociation of self-assembled β-amyloid aggregates into small, nontoxic fragments by ruthenium (II) complex
The self-assembly of β-amyloid (Aβ) peptides into highly stable plaques is a major hallmark
of Alzheimer's disease. Here, we report visible light-driven dissociation of β-sheet-rich Aβ …
of Alzheimer's disease. Here, we report visible light-driven dissociation of β-sheet-rich Aβ …
[HTML][HTML] Novel catalytically active Pd/Ru bimetallic nanoparticles synthesized by Bacillus benzeovorans
Bacillus benzeovorans assisted and supported growth of ruthenium (bio-Ru) and
palladium/ruthenium (bio-Pd@ Ru) core@ shell nanoparticles (NPs) as bio-derived …
palladium/ruthenium (bio-Pd@ Ru) core@ shell nanoparticles (NPs) as bio-derived …
[HTML][HTML] Emerging molecular receptors for the specific-target delivery of ruthenium and gold complexes into cancer cells
JF Machado, JDG Correia, TS Morais - Molecules, 2021 - mdpi.com
Cisplatin and derivatives are highly effective in the treatment of a wide range of cancer
types; however, these metallodrugs display low selectivity, leading to severe side effects …
types; however, these metallodrugs display low selectivity, leading to severe side effects …
Ru (II)/amino acid complexes inhibit the progression of breast cancer cells through multiple mechanism-induced apoptosis
F Mello-Andrade, APM Guedes, WC Pires… - Journal of Inorganic …, 2022 - Elsevier
For some cancer subtypes, such as triple-negative breast cancer, there are no specific
therapies, which leads to a poor prognosis associated with invasion and metastases …
therapies, which leads to a poor prognosis associated with invasion and metastases …