Aim Breast cancer is the most common cancer among women and one of the most important
causes of death among them. This review aimed to investigate the incidence and mortality …

The rates of obesity and diabetes are increasing worldwide, whereas the age of onset for
both obesity and diabetes are decreasing steadily. Obesity and diabetes are associated with …

To fully utilize the advances in omics technologies and achieve a more comprehensive
understanding of human diseases, novel computational methods are required for integrative …

Epidemiological studies demonstrate an association between breast cancer (BC) and
systemic dysregulation of glucose metabolism. However, how BC influences glucose …

The prevalence of obesity is rapidly increasing globally. Epidemiological studies have
associated obesity with a range of cancer types, although the mechanisms by which obesity …

Background Insulin-like growth factor (IGF)-I and its main binding protein, IGFBP-3,
modulate cell growth and survival, and are thought to be important in tumour development …

Background: Obesity is associated with increased breast cancer risk among
postmenopausal women. We examined whether this association could be explained by the …

The insulin-like growth factor 1 (IGF1) signalling pathway has important roles in regulating
cellular proliferation and apoptosis. Converging results from epidemiological research and …

BACKGROUND: Insulin-like growth factor 1 (IGF1) stimulates mitosis and inhibits apoptosis.
Some published results have shown an association between circulating IGF1 and breast …

Diabetes mellitus has been associated with an increased risk of several types of cancers,
but its relationship with breast cancer remains unclear. We conducted a meta‐analysis of …