The history of antimicrobial resistance (AMR) evolution and the diversity of the
environmental resistome indicate that AMR is an ancient natural phenomenon. Acquired …

Antimicrobial, and particularly antibiotic resistance are one of the world's biggest challenges
today, and urgent action is needed to reinvigorate the antibiotic development pipeline. To …

The rationing of health care is universal and inevitable, taking place in both poor and
affluent countries, in publicly funded and private health care systems. Someone must budget …

Highlights•Antimicrobial resistance is on the rise globally.•The pipeline for new antibiotics is
weak due to market failure.•New initiatives have been put in place to replenish the antibiotic …

This paper explores how the Resource Interaction Approach (RIA), namely the 4Rs model
and the three settings of developing-producing-using, can be applied to complex policy …

Abstract Helicobacter pylori (H. pylori), creating a global infection rate over 50%, presents
great challenges in clinical therapies due to its complex pathological microenvironment in …

Marine fungi represent a huge untapped resource of natural products. The bio‐activity of a
new asperbutenolide A from marine fungus Aspergillus terreus was not well known. In the …

Abstract On 16 July, 2019, the US Food and Drug Administration approved imipenem–
cilastatin/relebactam (Recarbrio™) for the treatment of adults with complicated urinary tract …

Humanity is facing a global threat caused by growing antibiotic resistance. If the current lack
of innovation in antibiotics persists, we will face a doomsday scenario with drastic …

Ferrous iron and polysulfide (Fe (II) S n aq) is a nano‐decoction. It is usually prepared from
the suspension of iron sulfide nanomaterial, using autoclave and centrifugation. A previous …