Insulin resistance is increasingly recognized as a chronic, low-level, inflammatory state.
Hyperinsulinemia and insulin action were initially proposed as the common preceding …

Osteoporosis is associated with increased morbidity, mortality and significant economic and
health costs. Vitamin D is a secosteriod hormone essential for calcium absorption and bone …

Osteoporosis is substantially an age-related condition characterized by low bone mass and
increased bone fragility, putting the patients at risk of fractures, which are major causes of …

C-reactive protein (CRP) is an acute-phase serum protein and a member of the pentraxin
protein family. Its host defense functions predate the adaptive immune system by millions of …

Reports of the predictive value of minor elevation of serum C-reactive protein (CRP) levels
(between 3 and 10 mg/L) for atherosclerotic events have generated considerable interest, as …

Low‐grade inflammation, a minor elevation in the baseline concentration of inflammatory
markers such as C‐reactive protein (CRP), is nowadays recognized as an important …

Rheumatoid arthritis (RA) is a chronic, systemic, inflammatory, multi-factorial disease
sustained by environmental and genetic factors. These seem to be necessary but not …

With advancing age, the balance between the amounts of old bone removed and new bone
formed during the remodelling process becomes negative. In the past, it was commonly …

Osteoporosis is, an age related disorder, influencing elderly people worldwide. The latest
data suggests that inflammation plays a critical role in bone remodeling and in pathogenesis …

Stature, bone size, and bone mass are interrelated traits with high heritability, but the major
genes that govern these phenotypes remain unknown. Independent genomewide …