Sphingolipids in obesity and correlated co-morbidities: the contribution of gender, age and environment
E Torretta, P Barbacini, NM Al-Daghri… - International Journal of …, 2019 - mdpi.com
This paper reviews our present knowledge on the contribution of ceramide (Cer),
sphingomyelin (SM), dihydroceramide (DhCer) and sphingosine-1-phosphate (S1P) in …
sphingomyelin (SM), dihydroceramide (DhCer) and sphingosine-1-phosphate (S1P) in …
A rationale for hypoxic and chemical conditioning in Huntington's disease
J Burtscher, V Maglione, A Di Pardo, GP Millet… - International Journal of …, 2021 - mdpi.com
Neurodegenerative diseases are characterized by adverse cellular environments and
pathological alterations causing neurodegeneration in distinct brain regions. This …
pathological alterations causing neurodegeneration in distinct brain regions. This …
Sphingosine‐1‐phosphate in mitochondrial function and metabolic diseases
M Duan, P Gao, S Chen, P Novák, K Yin… - Obesity …, 2022 - Wiley Online Library
Summary Sphingosine‐1‐phosphate (S1P) is a bioactive sphingolipid metabolite. The past
decade has witnessed exponential growth in the field of S1P research, partly attributed to …
decade has witnessed exponential growth in the field of S1P research, partly attributed to …
[HTML][HTML] A current view of G protein-coupled receptor-mediated signaling in pulmonary hypertension: finding opportunities for therapeutic intervention
D Strassheim, V Karoor, K Stenmark, A Verin… - Vessel Plus, 2018 - ncbi.nlm.nih.gov
Pathological vascular remodeling is observed in various cardiovascular diseases including
pulmonary hypertension (PH), a disease of unknown etiology that has been characterized …
pulmonary hypertension (PH), a disease of unknown etiology that has been characterized …
Hypoxia-induced inflammation: Profiling the first 24-hour posthypoxic plasma and central nervous system changes
LA Mesentier-Louro, B Rangel, L Stell, MA Shariati… - PloS one, 2021 - journals.plos.org
Central nervous system and visual dysfunction is an unfortunate consequence of systemic
hypoxia in the setting of cardiopulmonary disease, including infection with SARS-CoV-2 …
hypoxia in the setting of cardiopulmonary disease, including infection with SARS-CoV-2 …
Preventive preclinical efficacy of intravenously administered sphingosine-1-phosphate (S1P) in strengthening hypoxia adaptive responses to acute and sub-chronic …
Abstract Sphingosine-1-phosphate (S1P) is emerging as a hypoxia responsive bio-lipid;
systemically raised levels of S1P are proposed to have potential hypoxia pre-conditioning …
systemically raised levels of S1P are proposed to have potential hypoxia pre-conditioning …
Signaling controversy and future therapeutical perspectives of targeting sphingolipid network in cancer immune editing and resistance to tumor necrosis factor-α …
OA Sukocheva, ME Neganova, Y Aleksandrova… - Cell Communication and …, 2024 - Springer
Anticancer immune surveillance and immunotherapies trigger activation of cytotoxic cytokine
signaling, including tumor necrosis factor-α (TNF-α) and TNF-related apoptosis-inducing …
signaling, including tumor necrosis factor-α (TNF-α) and TNF-related apoptosis-inducing …
Sphingosine 1-phosphate in sepsis and beyond: its role in disease tolerance and host defense and the impact of carrier molecules
AC Ziegler, T Müller, MH Gräler - Cellular Signalling, 2021 - Elsevier
Abstract Sphingosine 1-phosphate (S1P) is an important immune modulator responsible for
physiological cellular responses like lymphocyte development and function, positioning and …
physiological cellular responses like lymphocyte development and function, positioning and …
Effects of S1PR2 antagonist on blood pressure and angiogenesis imbalance in preeclampsia rats
T Zhang, D Guo, W Zheng… - Molecular Medicine …, 2021 - spandidos-publications.com
Preeclampsia (PE), a hypertensive multisystem disorder, can lead to increased maternal
and fetal mortality and morbidity. Sphingosine‑1‑phosphate (S1P) plays various roles …
and fetal mortality and morbidity. Sphingosine‑1‑phosphate (S1P) plays various roles …
[HTML][HTML] Pharmacological approaches to limit ischemic and reperfusion injuries of the heart: analysis of experimental and clinical data on P2Y12 receptor antagonists
LN Maslov, SV Popov… - Korean Circulation …, 2022 - synapse.koreamed.org
Ischemic and reperfusion injuries of the heart underlie the pathogenesis of acute myocardial
infarction (AMI) and sudden cardiac death. The mortality rate is still high and is 5–7% in …
infarction (AMI) and sudden cardiac death. The mortality rate is still high and is 5–7% in …