Lyme borreliosis–from tick bite to diagnosis and treatment

G Stanek, F Strle - FEMS microbiology reviews, 2018 - academic.oup.com
Lyme borreliosis is caused by certain genospecies of the Borrelia burgdorferi sensu lato
complex, which are transmitted by hard ticks of the genus Ixodes. The most common clinical …

The Brilliance of Borrelia: Mechanisms of Host Immune Evasion by Lyme Disease-Causing Spirochetes

C Anderson, CA Brissette - Pathogens, 2021 - mdpi.com
Lyme disease (LD) has become the most common vector-borne illness in the northern
hemisphere. The causative agent, Borrelia burgdorferi sensu lato, is capable of establishing …

Clinical manifestations and diagnosis of Lyme borreliosis

F Strle, G Stanek - Lyme Borreliosis, 2009 - karger.com
Lyme borrelosis is a multi-systemic disease caused byBorrelia burgdorferisensu lato. A
complete presentation of the disease is an extremely unusual oberservation, in which a skin …

Hidden in plain sight: Borrelia burgdorferi and the extracellular matrix

FC Cabello, HP Godfrey, SA Newman - Trends in microbiology, 2007 - cell.com
Borrelia burgdorferi, the tick-transmitted etiologic agent of Lyme borreliosis, can colonize
and persist in multiple tissue sites despite vigorous host immune responses. The …

Human Coinfection with Borrelia burgdorferi and Babesia microti in the United States

KL Knapp, NA Rice - Journal of parasitology research, 2015 - Wiley Online Library
Borrelia burgdorferi, the causative agent of Lyme disease, and Babesia microti, a causative
agent of babesiosis, are increasingly implicated in the growing tick‐borne disease burden in …

Shift from Toll‐like receptor 2 (TLR‐2) toward TLR‐4 dependency in the erosive stage of chronic streptococcal cell wall arthritis coincident with TLR‐4–mediated …

S Abdollahi‐Roodsaz, LAB Joosten… - … : Official Journal of …, 2008 - Wiley Online Library
Abstract Objective Toll‐like receptors (TLRs) may activate innate and adaptive immune
responses in rheumatoid arthritis (RA) through recognition of microbial as well as …

Lyme arthritis: pathogenesis, clinical presentation, and management

YA Puius, RA Kalish - Infectious disease clinics of North America, 2008 - Elsevier
Arthritis is one of the most prominent features of Lyme disease, the tick-borne illness caused
by Borrelia burgdorferi. Although the pathogenesis of Lyme arthritis is complex and still …

Antialarmin effect of tick saliva during the transmission of Lyme disease

C Marchal, F Schramm, A Kern, BJ Luft… - Infection and …, 2011 - Am Soc Microbiol
Tick saliva has potent immunomodulatory properties. In arthropod-borne diseases, this effect
is largely used by microorganisms to increase their pathogenicity and to evade host immune …

Recruitment of macrophages and polymorphonuclear leukocytes in Lyme carditis

RR Montgomery, CJ Booth, X Wang… - Infection and …, 2007 - Am Soc Microbiol
Lyme arthritis, caused by the spirochete Borrelia burgdorferi, can be recurrent or prolonged,
whereas Lyme carditis is mostly nonrecurring. A prominent difference between arthritis and …

Borrelia burgdorferi infection regulates CD1 expression in human cells and tissues via IL1‐β

K Yakimchuk, C Roura‐Mir… - European journal of …, 2011 - Wiley Online Library
The appearance of group 1 CD1 proteins (CD1a, CD1b and CD1c) on maturing myeloid DC
is a key event that converts myeloid DC to effective lipid APC. Here, we show that Borrelia …