Emerging biomarkers, tools, and treatments for diabetic polyneuropathy

GJ Bönhof, C Herder, A Strom, N Papanas… - Endocrine …, 2019 - academic.oup.com
Diabetic neuropathy, with its major clinical sequels, notably neuropathic pain, foot ulcers,
and autonomic dysfunction, is associated with substantial morbidity, increased risk of …

[HTML][HTML] Diabetic complications in the cornea

AV Ljubimov - Vision research, 2017 - Elsevier
Diabetic corneal alterations, such as delayed epithelial wound healing, edema, recurrent
erosions, neuropathy/loss of sensitivity, and tear film changes are frequent but …

Mechanistic investigations of diabetic ocular surface diseases

Q Zhou, L Yang, Q Wang, Y Li, C Wei… - Frontiers in …, 2022 - frontiersin.org
With the global prevalence of diabetes mellitus over recent decades, more patients suffered
from various diabetic complications, including diabetic ocular surface diseases that may …

A systematic review on the impact of diabetes mellitus on the ocular surface

K Shih, KSL Lam, L Tong - Nutrition & diabetes, 2017 - nature.com
Diabetes mellitus is associated with extensive morbidity and mortality in any human
community. It is well understood that the burden of diabetes is attributed to chronic …

Early detection of diabetic peripheral neuropathy: a focus on small nerve fibres

J Burgess, B Frank, A Marshall, RS Khalil, G Ponirakis… - Diagnostics, 2021 - mdpi.com
Diabetic peripheral neuropathy (DPN) is the most common complication of both type 1 and 2
diabetes. As a result, neuropathic pain, diabetic foot ulcers and lower-limb amputations …

Systemic diseases and the cornea

R Shah, C Amador, K Tormanen, S Ghiam… - Experimental eye …, 2021 - Elsevier
There is a number of systemic diseases affecting the cornea. These include endocrine
disorders (diabetes, Graves' disease, Addison's disease, hyperparathyroidism), infections …

Normative values for corneal nerve morphology assessed using corneal confocal microscopy: a multinational normative data set

M Tavakoli, M Ferdousi, IN Petropoulos, J Morris… - Diabetes …, 2015 - Am Diabetes Assoc
OBJECTIVE Corneal confocal microscopy is a novel diagnostic technique for the detection
of nerve damage and repair in a range of peripheral neuropathies, in particular diabetic …

Corneal confocal microscopy predicts the development of diabetic neuropathy: a longitudinal diagnostic multinational consortium study

BA Perkins, LE Lovblom, EJH Lewis, V Bril… - Diabetes …, 2021 - Am Diabetes Assoc
OBJECTIVE Corneal nerve fiber length (CNFL) has been shown in research studies to
identify diabetic peripheral neuropathy (DPN). In this longitudinal diagnostic study, we …

Corneal confocal microscopy for the diagnosis of diabetic peripheral neuropathy: A systematic review and meta‐analysis

H Gad, IN Petropoulos, A Khan… - Journal of diabetes …, 2021 - pmc.ncbi.nlm.nih.gov
Introduction Corneal confocal microscopy (CCM) is a rapid non‐invasive ophthalmic
imaging technique that identifies corneal nerve fiber damage. Small studies suggest that …

Diabetic keratopathy: redox signaling pathways and therapeutic prospects

F Buonfiglio, J Wasielica-Poslednik, N Pfeiffer… - Antioxidants, 2024 - mdpi.com
Diabetes mellitus, the most prevalent endocrine disorder, not only impacts the retina but also
significantly involves the ocular surface. Diabetes contributes to the development of dry eye …