Microtubules are essential dynamic polymers composed of α/β-tubulin heterodimers. They
support intracellular trafficking, cell division, cellular motility, and other essential cellular …

The endoplasmic reticulum (ER) is a continuous, highly dynamic membrane compartment
that is crucial for numerous basic cellular functions. The ER stretches from the nuclear …

It is widely known that stimulator of interferon genes (STING) can trigger nuclear factor κB
(NF-κB) signaling. However, whether and how the NF-κB pathway affects STING signaling …

Cells respond to fluctuating nutrient supply by adaptive changes in organelle dynamics and
in metabolism. How such changes are orchestrated on a cell-wide scale is unknown. We …

Developing a multifunctional nanoplatform to achieve efficient theranostics of tumors
through multi‐pronged strategies remains to be challenging. Here, the design of the …

The cytoplasm is highly organized. However, the extent to which this organization influences
the dynamics of cytoplasmic proteins is not well understood. Here, we use Xenopus laevis …

Proteotoxic stress causes profound endoplasmic reticulum (ER) membrane remodeling into
a perinuclear quality control compartment (ERQC) for the degradation of misfolded proteins …

The dynamic distribution of the microtubule (MT) cytoskeleton is crucial for the shape,
motility, and internal organization of eukaryotic cells. However, the basic principles that …

Microtubules, a critical component of the cytoskeleton, carry post-translational modifications
(PTMs) that are important for the regulation of key cellular processes. Long-lived …

The complex architecture of the endoplasmic reticulum (ER) comprises distinct dynamic
features, many at the nanoscale, that enable the coexistence of the nuclear envelope …